Results 61 to 70 of about 118,109 (263)

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Robust and Accurate Curvature Estimation Using Adaptive Line Integrals

open access: yesEURASIP Journal on Advances in Signal Processing, 2010
The task of curvature estimation from discrete sampling points along a curve is investigated. A novel curvature estimation algorithm based on performing line integrals over an adaptive data window is proposed.
Chiu Yen-Lin   +4 more
doaj  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Algebraic Properties of Curvature Operators in Lorentzian Manifolds with Large Isometry Groups

open access: yesSymmetry, Integrability and Geometry: Methods and Applications, 2010
Together with spaces of constant sectional curvature and products of a real line with a manifold of constant curvature, the socalled Egorov spaces and ε-spaces exhaust the class of n-dimensional Lorentzian manifolds admitting a group of isometries of ...
Giovanni Calvaruso, Eduardo García-Río
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Research on Curvature Interference Characteristics of Conical Surface Enveloping Cylindrical Worm–Face Worm Gear Drive

open access: yesApplied Sciences
This study proposes the use of Physics-Informed Neural Networks (PINNs) to further advance the curvature interference analysis method. The nonlinear equation system encountered in determining the curvature interference limit line is embedded into the ...
Shibo Mu   +8 more
doaj   +1 more source

Impact of radius and skew angle on areal density in heat assisted magnetic recording hard disk drives

open access: yesAIP Advances, 2018
This study aims to investigate the impact that factors such as skew, radius, and transition curvature have on areal density capability in heat-assisted magnetic recording hard disk drives. We explore a “ballistic seek” approach for capturing in-situ scan
Michael Cordle   +6 more
doaj   +1 more source

α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates

open access: yesFEBS Letters, EarlyView.
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino   +2 more
wiley   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Proposal for a transition curve with smoothly changing curvature using multiple clothoid curve (Third report: Application to a lane change)

open access: yesNihon Kikai Gakkai ronbunshu, 2019
This paper presents theoretical research on an optimum transition curve with a smoothly changing curvature using a multiple clothoid curve for improving the occupant ride comfort of automobiles when vehicle changes a lane from a traveling lane to a ...
Makoto YAMAMOTO, Shuji NISHIYAMA
doaj   +1 more source

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