Results 61 to 70 of about 168,150,866 (290)

A cell model in the ventral visual pathway for the detection of circles of curvature constituting figures

open access: yesHeliyon, 2020
The contour of an arbitrary figure can be represented as a group of circles of curvature in contact with it, with each curvature circle represented by its center OC and radius r.
Susumu Kawakami   +4 more
doaj   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Algebraic Properties of Curvature Operators in Lorentzian Manifolds with Large Isometry Groups

open access: yesSymmetry, Integrability and Geometry: Methods and Applications, 2010
Together with spaces of constant sectional curvature and products of a real line with a manifold of constant curvature, the socalled Egorov spaces and ε-spaces exhaust the class of n-dimensional Lorentzian manifolds admitting a group of isometries of ...
Giovanni Calvaruso, Eduardo García-Río
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Research on Curvature Interference Characteristics of Conical Surface Enveloping Cylindrical Worm–Face Worm Gear Drive

open access: yesApplied Sciences
This study proposes the use of Physics-Informed Neural Networks (PINNs) to further advance the curvature interference analysis method. The nonlinear equation system encountered in determining the curvature interference limit line is embedded into the ...
Shibo Mu   +8 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Mean Curvature Flow with a Neumann Boundary Condition in Flat Spaces [PDF]

open access: yes, 2012
In this thesis I study mean curvature flow in both Euclidean and Minkowski space with a Neumann boundary condition. In Minkowski space I show that for a convex timelike cone boundary condition, with compatible spacelike initial data, mean curvature flow
LAMBERT, BENJAMIN,STEPHEN
core  

Relaxation of thermal stress by dislocation motion in passivated metal interconnects [PDF]

open access: yes, 2004
The development and relaxation of stress in metal interconnects strained by their surroundings (substrate and passivation layers) is predicted by a discrete dislocation analysis.
Giessen, Erik van der,   +9 more
core   +2 more sources

Impact of radius and skew angle on areal density in heat assisted magnetic recording hard disk drives

open access: yesAIP Advances, 2018
This study aims to investigate the impact that factors such as skew, radius, and transition curvature have on areal density capability in heat-assisted magnetic recording hard disk drives. We explore a “ballistic seek” approach for capturing in-situ scan
Michael Cordle   +6 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

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