Results 211 to 220 of about 8,079,770 (310)

Tsunamigenic fault structures revealed in the 2024 Noto earthquake (M7.6) rupture area. [PDF]

Sci Rep
Park JO, Mohammadigheymasi H, Yamaguchi A, Okino K, Fujie G, Jamali Hondori E, Arikawa T, Kurihara T, Imai K.   +8 more
europepmc   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Depression symptom profiles and associated sociodemographic factors among perinatal women: A latent profile analysis. [PDF]

Aten Primaria
Xue C, Liu J, Shao H, Tu S.
europepmc   +1 more source

Line profiles in expanding envelopes

, 1979
An attempt is made to show how the physical and geometrical parameters prevailing in an expanding stellar envelope can be inferred from an analysis of one or more observed line profiles. Attention is given to the Sobolev approximation, line formation in outwardly accelerating envelopes, effects of a stellar core, and radiative transfer in outwardly ...
openaire   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

FourierDrug: a domain generalization framework for robust drug response prediction via frequency-space asymmetric attention. [PDF]

Bioinformatics
Song R, Bai Y, Liu X, Liu H.
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

GRIP-Lung: Generative Model of Response to Drug-Induced Perturbation in Lung Cancer. [PDF]

Int J Mol Sci
Fu Z, Li Y, Du Z, Zhang D, Liu L, Jin Q, Chen X, Xie H.   +7 more
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Blood-based kinase activity profiling to predict response to immune checkpoint inhibitors in patients with advanced stage NSCLC: the prospective IOpener study. [PDF]

J Immunother Cancer
de Joode K, Groen HJ, Heuvel MVD, Kloover JS, Van Der Meer F, Van der Leest CH, Van Den Borne B, De Wijn R, Hurkmans DP, Van den Heuvel DMA, Pinedo HM, Kapiteijn E, Debets R, Verdegaal EME, Van der Burg SH, Groten JP, Aerts JGJV, Mathijssen RHJ.   +17 more
europepmc   +1 more source