Results 111 to 120 of about 10,265,072 (333)
AxiomsAn upgrade to the quasi-Newton (QN) family of methods for solving unconstrained optimization problems is proposed. This research focuses on a detailed investigation of the Barzilai and Borwein (BB) gradient methods.
Predrag S. Stanimirović +3 more
doaj +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Euphemisms and dysphemism: in search of a boundary line
Círculo de Lingüística Aplicada a la Comunicación, 2011 Straightforward remarks may sometimes be regarded as either an offence or an indelicacy. That is the reason why, to avoid the danger of being perceived vulgar or illmannered, language users prefer to employ a range of so-called concealing mechanisms ...
Bożena Duda
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Probabilistic Line Searches for Stochastic Optimization
, 2015 12 pages, including ...
Mahsereci, M., Hennig, P.
openaire +6 more sources
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Joint trade-off optimization algorithm based on cooperative spectrum sensing throughput
Tongxin xuebao, 2011 The achievable data throughput of the cognitive network was modeled to optimize the overhead and performance of the cooperative system thoroughly.Considering the soft data combination decision,the joint trade-off optimization of the local sampling number
Guo-qing JI, Gang WANG, Hong-bo ZHU
doaj
An Efficient Penalty Method without a Line Search for Nonlinear Optimization
AxiomsIn this work, we integrate some new approximate functions using the logarithmic penalty method to solve nonlinear optimization problems. Firstly, we determine the direction by Newton’s method.
Assma Leulmi
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A submillimetre wavelength spectral line search of the Orion molecular cloud core [PDF]
, 1986 A submillimetre wavelength molecular line search of the Orion molecular cloud has been made covering a total of about 5 percent of the frequency range 342.8 - 358.6 GHz.
Griffin, M. J. +4 more
core
Adaptive Backtracking Line Search
Backtracking line search is foundational in numerical optimization. The basic idea is to adjust the step-size of an algorithm by a constant factor until some chosen criterion (e.g. Armijo, Descent Lemma) is satisfied. We propose a novel way to adjust step-sizes, replacing the constant factor used in regular backtracking with one that takes into account
Cavalcanti, Joao V. +2 more
openaire +2 more sources