Results 101 to 110 of about 4,101,702 (289)

A novel three-term conjugate gradient approach for deep neural network training [PDF]

open access: yesIranian Journal of Numerical Analysis and Optimization
This paper presents a new three-term conjugate gradient (CG) method for large-scale unconstrained optimization, with application to training deep neural networks.
Faeze Sadat Hosseini-Mighan, Ali Ashrafi
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Improvement of Barzilai and Borwein Gradient Method Based on Neutrosophic Logic System with Application in Image Restoration

open access: yesAxioms
An upgrade to the quasi-Newton (QN) family of methods for solving unconstrained optimization problems is proposed. This research focuses on a detailed investigation of the Barzilai and Borwein (BB) gradient methods.
Predrag S. Stanimirović   +3 more
doaj   +1 more source

SEARCH FOR GRAVITATIONALLY REDSHIFTED 2.2 MEV LINE FROM 4U 1820-30 [PDF]

open access: yes, 2007
We have analyzed 1.7 Ms of the INTEGRAL data of the Low Mass X-Ray Binary (LMXB) 4U 1820-30 and searched for the redshifted 2.2 MeV neutron capture gamma-ray line.
Boggs, Steven E.   +3 more
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Euphemisms and dysphemism: in search of a boundary line

open access: yesCírculo de Lingüística Aplicada a la Comunicación, 2011
Straightforward remarks may sometimes be regarded as either an offence or an indelicacy. That is the reason why, to avoid the danger of being perceived vulgar or illmannered, language users prefer to employ a range of so-called concealing mechanisms ...
Bożena Duda
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

A submillimetre wavelength spectral line search of the Orion molecular cloud core [PDF]

open access: yes, 1986
A submillimetre wavelength molecular line search of the Orion molecular cloud has been made covering a total of about 5 percent of the frequency range 342.8 - 358.6 GHz.
Griffin, M. J.   +4 more
core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Joint trade-off optimization algorithm based on cooperative spectrum sensing throughput

open access: yesTongxin xuebao, 2011
The achievable data throughput of the cognitive network was modeled to optimize the overhead and performance of the cooperative system thoroughly.Considering the soft data combination decision,the joint trade-off optimization of the local sampling number
Guo-qing JI, Gang WANG, Hong-bo ZHU
doaj  

Home - About - Disclaimer - Privacy