Results 41 to 50 of about 7,604,005 (288)
Pediatric Blood &Cancer, EarlyView.ABSTRACT We assessed the effect of iron overload (IO) on mortality and complications following hematopoietic stem cell transplantation (HSCT) in patients with Diamond–Blackfan anemia syndrome (DBAS) in a systematic review of individual participant data and cohort data from observational studies.
Geoffrey Z. L. Kuppens +6 more
wiley +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Mathematics, 2018 In this paper, three-step Taylor expansion, which is equivalent to third-order Taylor expansion, is used as a mathematical base of the new descent method. At each iteration of this method, three steps are performed.
Mina Torabi, Mohammad-Mehdi Hosseini
doaj +1 more source
Search and Knowledge in Lines of Action [PDF]
, 2004 This paper describes the design and development of two world-class Lines of Action game-playing programs: YL, a three time Computer Olympiad gold-medal winner, and Mona, which has dominated international e-mail correspondence play. The underlying design philosophy of the two programs is very different: the former emphasizes fast and efficient search ...
Darse Billings, Yngvi Björnsson
openaire +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Inspired by the diverse set of technologies used in underground object detection and imaging, we introduce a novel multimodal linear search problem whereby a single searcher starts at the origin and must find a target that can only be detected when the searcher moves through its location using the correct of $p$ possible search modes.
Jared Coleman +4 more
openaire +2 more sources
Line search for averaged operator iteration [PDF]
2016 IEEE 55th Conference on Decision and Control (CDC), 2016 Many popular first order algorithms for convex optimization, such as forward-backward splitting, Douglas-Rachford splitting, and the alternating direction method of multipliers (ADMM), can be formulated as averaged iteration of a nonexpansive mapping.
Pontus Giselsson +2 more
openaire +2 more sources
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
MathematicsUnconstrained optimization problems have a long history in computational mathematics and have been identified as being among the crucial problems in the fields of applied sciences, engineering, and management sciences. In this paper, a new variant of the
Aliyu Muhammed Awwal +3 more
doaj +1 more source