Results 51 to 60 of about 7,898,408 (287)
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
MathematicsUnconstrained optimization problems have a long history in computational mathematics and have been identified as being among the crucial problems in the fields of applied sciences, engineering, and management sciences. In this paper, a new variant of the
Aliyu Muhammed Awwal +3 more
doaj +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
A Combined Cubic and Novel Line Search CG-Algorithm [PDF]
Al-Rafidain Journal of Computer Sciences and Mathematics, 2012 In this paper a new line search technique is investigated. It uses (cubic and novel) line searches in the standard CG-algorithm for unconstrained optimization.
Abbas Al-Bayati, Hamsa Chilmerane
doaj +1 more source
Searching for Emission-Line Galaxies [PDF]
International Astronomical Union Colloquium, 1984 Survey methods for finding emission-line galaxies are reviewed. Observational selection effects are investigated by comparing different surveys and the limitations of the different techniques are discussed. The advantages of Ha surveys for finding low luminosity galaxies and those with low excitation emission spectra are emphasized.
openaire +1 more source
Line and cell searching in tables or forms [PDF]
, 1995 Item searching is an important step in form analysis. The goal of this paper is to describe a robust method to locate the items whose boundaries are black lines, and an algorithm to classify those items. Our method is based on detection of lines by Hough transform and on searching of cycles in a graph that represents the cells (boundaries of the items).
E. Turolla +2 more
openaire +2 more sources
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
A New Preconditioned Inexact Line-Search Technique for Unconstrained Optimization [PDF]
, 2012 In this paper, we study the global convergence properties of the new class of preconditioned conjugate gradient descent algorithm, when applied to convex objective non-linear unconstrained optimization functions.
Ivan Latif, Abbas Al-Bayati
core +1 more source
Faster Convergence for Transformer Fine-tuning with Line Search Methods [PDF]
, 2023 Kenneweg P, Galli L, Kenneweg T, Hammer B. Faster Convergence for Transformer Fine-tuning with Line Search Methods. In: 2023 International Joint Conference on Neural Networks (IJCNN).
Hammer, Barbara ; https://orcid.org/ +5 more
core +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source