Results 111 to 120 of about 19,833 (300)
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
The most important step in plant breeding is the correct selection of parents, and it would be wise to use heterotic groups for this. The purpose of this study is to analyse yield and its components as well as genetic diversity in line x tester wheat ...
Kutlu, Imren +2 more
core +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
, 2017 Bu araştırma, özellikle Trakya Bölgesi (Edirne, Tekirdağ ve Kırklareli) için melezlerden geliştirilmiş 12 ileri ekmeklik buğday hattı (3 doubled haploid hat, 3 ileri hat, 3 mutant hat, 3 türler arası melez) ve 3 yaygın olarak yetiştirilen ticari çeşit ...
DEVİREN, Birol
core
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
, 1995 Bu çalışma ayçiçeğinde 6 ana (CMS) hat ve 3 baba (restorer) testerin genel ve özel kombinasyon kabiliyetini tahmin etmek ve iyi verim verme kapasitesine sahip olan yeni F1 hibridlerini belirlemek için yürütülmüştür. Çalışmada kullanılan ebeveynler Uludağ
core
, 2010 CO446 is a short-season corn (Zea mays L.) inbred line with excellent combining ability and lodging resistance in hybrids. This inbred performed well as a parent with both stiff and non-stiff stalk inbreds.
L. M. Reid, X. Zhu
core +1 more source
Heterosis in relation to combining ability for yield and quality attributes in Brinjal (Solanum melongena L.) [PDF]
Electronic Journal of Plant Breeding, 2010 Genetical studies on fruit yield per plant and its attributing traits alongwith quality traits like total soluble solids (TSS) andrind thickness were conducted following line x tester mating design comprising of 8 lines and 6 testers at ...
Abhinav Sao and Nandan Mehta
doaj
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source