Results 91 to 100 of about 137,568 (296)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

AVALIAÇÃO DE LINHAGENS S3 DE MILHO POR MEIO DE TESTADORES ADAPTADOS À SAFRINHA

Revista Caatinga, 2015
Several breeding programs aim to develop superior maize genotypes able to be explored in off-season cropping, mainly due to the increased area under maize produced in alternative season.
LUIZ RAFAEL CLOVIS, CARLOS ALBERTO SCAPIM, RONALD JOSÉ BARTH PINTO, EDSON BOLSON, HENRIQUE JOSÉ CAMARGO SENHORINHO   +4 more
doaj  

Testing Piecewise Functions

, 2018
This work explores the query complexity of property testing for general piecewise functions on the real line, in the active and passive property testing settings.
Hanneke, Steve, Yang, Liu
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Heterosis in relation to combining ability for yield and quality attributes in Brinjal (Solanum melongena L.) [PDF]

Electronic Journal of Plant Breeding, 2010
Genetical studies on fruit yield per plant and its attributing traits alongwith quality traits like total soluble solids (TSS) andrind thickness were conducted following line x tester mating design comprising of 8 lines and 6 testers at ...
Abhinav Sao and Nandan Mehta
doaj  

The anther-culture response of triticale line x tester progenies.

Cellular & molecular biology letters, 2004
Seven triticale cultivars (Ampiac, Aubrac, Trinidad, Ticino, Lamberto, Pronto and Prado) and their F1 hybrids obtained after crossing in a line x tester scheme were examined with respect to their androgenetic effectiveness. The embryo induction rate (number of embryos per 100 anthers), green plant regeneration rate (number of green plantlets per 100 ...
Karol, Marciniak, Zygmunt, Kaczmarek, Tadeusz, Adamski, Maria, Surma   +3 more
openaire   +1 more source

Combining Ability Estimates from Line x Tester Mating Design in Upland Cotton

Journal of Basic & Applied Sciences, 2016
Combining abilities of cotton varieties were evaluated using a line x tester mating design, twelve hybridswhich developed from 3 testers (male) and 4 lines (females). The experiment was conducted on Randomized Complete Block Design (RCBD) with three replications during 2014. The data were recorded for plant height, sympodial plant-1, bollsplant-1, boll
null Mir Yar Mohammad Talpur, null Shabana Memon, null Sadaf Memon, null Shah Nawaz Mari, null Sawan Laghari, null Zahoor Ahmed Soomro, null Samia Arain, null Washu Dev, null Aamir Ali Abro, null Saifullah Abro   +9 more
openaire   +1 more source

Tracing the early development of harmful algal blooms with the aid of Lagrangian coherent structures

, 2007
Several theories have been proposed to explain the development of harmful algal blooms (HABs) produced by the toxic dinoflagellate \emph{Karenia brevis} on the West Florida Shelf.
F. J. Beron-vera, H. Koçak, L. E. Br, L. E. Brand Rsmas/amp, M. J. Olascoaga   +4 more
core   +2 more sources