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First insights into the phylogenetic diversity of Mycobacterium tuberculosis in Nepal [PDF]

open access: yes, 2012
BACKGROUND: Tuberculosis (TB) is a major public health problem in Nepal. Strain variation in Mycobacterium tuberculosis may influence the outcome of TB infection and disease. To date, the phylogenetic diversity of M.
A Sandgren   +67 more
core   +17 more sources

BMP4 drives primed to naïve transition through PGC-like state

open access: yesNature Communications, 2022
Multiple pluripotent states have been described in mouse and human stem cells. Here the authors describe trajectories during BMP4 induced primed to naïve transition, which bifurcates into naïve and trophoblast-like branches with a PGC-like intermediate ...
Shengyong Yu   +26 more
doaj   +1 more source

INFLUENCE OF BREED AND COUNTRY OF ORIGIN ON INDICATORS OF SEMEN PRODUCTION OF STUD BULLS [PDF]

open access: yesVolga Region Farmland, 2021
The article presents data on the influence of the breed of linear affiliation, country of origin on the quality indicators of sperm production of sire bulls. The research was carried out on bulls of Holstein, Black Pied, Brown Swiss and Hereford bulls at
O.V. Rudenko, M. Almohammed
doaj   +1 more source

Structure Insights Into Photosystem I Octamer From Cyanobacteria

open access: yesFrontiers in Microbiology, 2022
The diversity of photosystem oligomers is essential to understanding how photosynthetic organisms adapt to light conditions. Due to its structural and physiological significance, the assembly of the PSI supercomplex has been of great interest recently in
Ming Chen   +11 more
doaj   +1 more source

Three-dimensional molecular architecture of mouse organogenesis

open access: yesNature Communications, 2023
Mammalian embryos exhibit sophisticated cellular patterning that is intricately orchestrated at both molecular and cellular level. It has recently become apparent that cells within the animal body display significant heterogeneity, both in terms of their
Fangfang Qu   +19 more
doaj   +1 more source

Lung development and regeneration: newly defined cell types and progenitor status

open access: yesCell Regeneration, 2023
The lung is the most critical organ of the respiratory system supporting gas exchange. Constant interaction with the external environment makes the lung vulnerable to injury.
Xiaogao Meng   +2 more
doaj   +1 more source

Control of RNA degradation in cell fate decision

open access: yesFrontiers in Cell and Developmental Biology, 2023
Cell fate is shaped by a unique gene expression program, which reflects the concerted action of multilayered precise regulation. Substantial research attention has been paid to the contribution of RNA biogenesis to cell fate decisions.
Mingqiang Deng   +5 more
doaj   +1 more source

Lineage Tracing [PDF]

open access: yesCell, 2012
Lineage tracing is the identification of all progeny of a single cell. Although its origins date back to developmental biology of invertebrates in the 19(th) century, lineage tracing is now an essential tool for studying stem cell properties in adult mammalian tissues.
Kretzschmar, Kai, Watt, Fiona M.
openaire   +2 more sources

scDIOR: single cell RNA-seq data IO software

open access: yesBMC Bioinformatics, 2022
Background Single-cell RNA sequencing is becoming a powerful tool to identify cell states, reconstruct developmental trajectories, and deconvolute spatial expression.
Huijian Feng, Lihui Lin, Jiekai Chen
doaj   +1 more source

The role of BMP4 in adipose-derived stem cell differentiation: A minireview

open access: yesFrontiers in Cell and Developmental Biology, 2022
Bone morphogenetic protein 4 (BMP4) is a member of the transforming growth factor beta (TGF-β) superfamily of cytokines responsible for stem cells’ commitment to differentiation, proliferation, and maturation.
Abdul Malik Setiawan   +3 more
doaj   +1 more source

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