Results 1 to 10 of about 1,050,104 (292)

BMP4 drives primed to naïve transition through PGC-like state

Nature Communications, 2022
Multiple pluripotent states have been described in mouse and human stem cells. Here the authors describe trajectories during BMP4 induced primed to naïve transition, which bifurcates into naïve and trophoblast-like branches with a PGC-like intermediate ...
Shengyong Yu, Chunhua Zhou, Jiangping He, Zhaokai Yao, Xingnan Huang, Bowen Rong, Hong Zhu, Shijie Wang, Shuyan Chen, Xialian Wang, Baomei Cai, Guoqing Zhao, Yuhan Chen, Lizhan Xiao, He Liu, Yue Qin, Jing Guo, Haokaifeng Wu, Zhen Zhang, Man Zhang, Xiaoyang Zhao, Fei Lan, Yixuan Wang, Jiekai Chen, Shangtao Cao, Duanqing Pei, Jing Liu   +26 more
doaj   +1 more source

Three-dimensional molecular architecture of mouse organogenesis

Nature Communications, 2023
Mammalian embryos exhibit sophisticated cellular patterning that is intricately orchestrated at both molecular and cellular level. It has recently become apparent that cells within the animal body display significant heterogeneity, both in terms of their
Fangfang Qu, Wenjia Li, Jian Xu, Ruifang Zhang, Jincan Ke, Xiaodie Ren, Xiaogao Meng, Lexin Qin, Jingna Zhang, Fangru Lu, Xin Zhou, Xi Luo, Zhen Zhang, Minhan Wang, Guangming Wu, Duanqing Pei, Jiekai Chen, Guizhong Cui, Shengbao Suo, Guangdun Peng   +19 more
doaj   +1 more source

INFLUENCE OF BREED AND COUNTRY OF ORIGIN ON INDICATORS OF SEMEN PRODUCTION OF STUD BULLS [PDF]

Volga Region Farmland, 2021
The article presents data on the influence of the breed of linear affiliation, country of origin on the quality indicators of sperm production of sire bulls. The research was carried out on bulls of Holstein, Black Pied, Brown Swiss and Hereford bulls at
O.V. Rudenko, M. Almohammed
doaj   +1 more source

Structure Insights Into Photosystem I Octamer From Cyanobacteria

Frontiers in Microbiology, 2022
The diversity of photosystem oligomers is essential to understanding how photosynthetic organisms adapt to light conditions. Due to its structural and physiological significance, the assembly of the PSI supercomplex has been of great interest recently in
Ming Chen, Yujie He, Dongyang Liu, Lijin Tian, Pengqi Xu, Xuan Liu, Yihang Pan, Shuqi Dong, Shuqi Dong, Jun He, Jun He, Ying Zhang   +11 more
doaj   +1 more source

Lung development and regeneration: newly defined cell types and progenitor status

Cell Regeneration, 2023
The lung is the most critical organ of the respiratory system supporting gas exchange. Constant interaction with the external environment makes the lung vulnerable to injury.
Xiaogao Meng, Guizhong Cui, Guangdun Peng   +2 more
doaj   +1 more source

Control of RNA degradation in cell fate decision

Frontiers in Cell and Developmental Biology, 2023
Cell fate is shaped by a unique gene expression program, which reflects the concerted action of multilayered precise regulation. Substantial research attention has been paid to the contribution of RNA biogenesis to cell fate decisions.
Mingqiang Deng, Mingqiang Deng, Xiwei Wang, Zhi Xiong, Zhi Xiong, Peng Tang   +5 more
doaj   +1 more source

scDIOR: single cell RNA-seq data IO software

BMC Bioinformatics, 2022
Background Single-cell RNA sequencing is becoming a powerful tool to identify cell states, reconstruct developmental trajectories, and deconvolute spatial expression.
Huijian Feng, Lihui Lin, Jiekai Chen
doaj   +1 more source

The role of BMP4 in adipose-derived stem cell differentiation: A minireview

Frontiers in Cell and Developmental Biology, 2022
Bone morphogenetic protein 4 (BMP4) is a member of the transforming growth factor beta (TGF-β) superfamily of cytokines responsible for stem cells’ commitment to differentiation, proliferation, and maturation.
Abdul Malik Setiawan, Abdul Malik Setiawan, Taty Anna Kamarudin, Norzana Abd Ghafar   +3 more
doaj   +1 more source

First insights into the phylogenetic diversity of Mycobacterium tuberculosis in Nepal [PDF]

, 2012
BACKGROUND: Tuberculosis (TB) is a major public health problem in Nepal. Strain variation in Mycobacterium tuberculosis may influence the outcome of TB infection and disease. To date, the phylogenetic diversity of M.
A Sandgren, AE Hirsh, AN Malik, BC de Jong, Bhagwan Maharjan, Bhawana Shrestha, Bijaya Malla, C Demay, CB Holmes, CB Uwizeye, Christophe Sola, D Stucki, David Stucki, E Lasunskaia, E Svensson, ES Click, F Brossier, FA Drobniewski, G Thwaites, H Dong, H Getahun, H Han, HY Dou, I Comas, I Parwati, J Kamerbeek, JK Bonfield, JR Sun, Julia Feldmann, K Brudey, K Brudey, L Baker, L Fenner, Lukas Fenner, M Caws, M Connolly, M Coscolla, M Hanekom, Markers European Concerted Action on New Generation Genetic, MM Gutacker, MW Borgdorff, N Lari, O Neyrolles, P Supply, P Supply, R Staden, RX Liu, S Borrell, S Borrell, S Feuerriegel, S Gagneux, S Gagneux, S Narayanan, S Niemann, S Sreevatsan, Sebastien Gagneux, Sonia Borrell, T Iwamoto, T Lillebaek, TC Victor, TN Buu, TN Buu, UB Singh, US Rajapaksa, Y Hu, Y Pang, YJ Sun, YL Guo   +67 more
core   +3 more sources

Genetic Variability in the E6/E7 Region of Human Papillomavirus 16 in Women from Ecuador

Viruses, 2023
Human Papillomavirus (HPV) infection is associated with intraepithelial neoplasia and cervical cancer (CC). Ecuador has a high prevalence of cervical cancer, with more than 1600 new cases diagnosed annually.
Alicia Zhingre, César Bedoya-Pilozo, Diana Gutiérrez-Pallo, Inés Badano, Andrés Herrera-Yela, Zoila Salazar, Damaris Alarcón, Natali Argüello-Bravo, Maylen Espinoza, Patricio Ponce, Yudira Soto, Andrés Carrazco-Montalvo   +11 more
doaj   +1 more source