Results 191 to 200 of about 1,099,358 (342)

Kidney Organoids in Drug Development: Integrating Technological Advances and Standardization for Effective Implementation

open access: yesAdvanced Healthcare Materials, EarlyView.
This review examines how emerging enabling technologies enhance the physiological relevance, scalability, and reproducibility of kidney organoids, while advanced analytical approaches support model validation and deepen mechanistic insight into nephrotoxicity.
Helen Kearney   +3 more
wiley   +1 more source

Author response: Oligodendrocyte-lineage cell exocytosis and L-type prostaglandin D synthase promote oligodendrocyte development and myelination

open access: gold, 2022
Lin Pan   +7 more
openalex   +1 more source

siRNA Delivery via Cross‐Linked Gelatin Microparticles Enables Targeted Modulation of Osteogenic‐Vascular Cross‐Talk: An Advanced Human 3D in Vitro Test System for Therapeutic siRNA

open access: yesAdvanced Healthcare Materials, EarlyView.
Osteogenic‐angiogenic cross‐talk is a vital prerequisite for vascularized bone regeneration. In this study, we investigated the effects of siRNA‐mediated silencing of two inhibitory proteins, Chordin and WWP‐1, via CaP‐NP‐loaded gelatin microparticles in osteogenically differentiated microtissues.
Franziska Mitrach   +7 more
wiley   +1 more source

New insights into the <i>Syllis prolifera</i> species complex from the eastern Mediterranean Sea. [PDF]

open access: yesZookeys
Belvis F   +4 more
europepmc   +1 more source

A Synovium‐on‐Chip Platform to Study Multicellular Interactions in Arthritis

open access: yesAdvanced Healthcare Materials, EarlyView.
The Synovium‐on‐Chip comprises a thin microporous PDMS membrane to support co‐culture of fibroblast‐like synoviocytes (FLS), THP‐1‐derived macrophages, and endothelial cells, enabling real‐time analysis of synovial‐vascular interactions. FLS migration through the pores drives endothelial remodeling, while TNF‐α stimulation induces robust inflammatory ...
Laurens R. Spoelstra   +8 more
wiley   +1 more source

Clonal Evolution and Lineage Switch from T-Cell Acute Lymphoblastic Leukemia to Acute Myeloid Leukemia in Therapy-Resistant <i>PICALM::MLLT10</i> Leukemia. [PDF]

open access: yesEJHaem
Kawamura M   +10 more
europepmc   +1 more source

Cell population analysis of the adult murine subependymal neurogenic lineage by flow cytometry

open access: gold, 2021
Germán Belenguer   +4 more
openalex   +1 more source

Home - About - Disclaimer - Privacy