Results 221 to 230 of about 1,050,104 (292)

Population Structure Analysis Reveals the Rich Genetic Diversity of Honeybee (<i>Apis mellifera</i> L.) Populations in Kazakhstan. [PDF]

Insects
Dossybayev K, Tapelov A, Nuraliyeva U, Moldakhmetova G, Kapassuly T, Kozhakhmet A, Krupskiy O, Torekhanov M, Taufikh A, Bekman D, Ualiyeva D, Kusza S, Amandykova M, Bekmanov B.   +13 more
europepmc   +1 more source

Telomere‐to‐Telomere Genomes Reveal that Multiscale Evolution Shapes the Largest Metabolic Arsenal of Diaporthe Fungi

Advanced Science, EarlyView.
This study presents the first telomere‐to‐telomere genomes and population resources for Diaporthe pathogens, uncovering the largest known fungal repertoire of secondary metabolite gene clusters. Structural variations and horizontal gene transfer drive cluster diversification, while specific rapidly evolving clusters control virulence, offering novel ...
Kainan Li, Chen Zhang, Zhichao Zhang, Jiaheng Cheng, Qiuyan Gao, Long Gao, Xiaolin Zhao, Wei Yan, Yuanchao Wang, Wenwu Ye   +9 more
wiley   +1 more source

The effect of increased weight loading on body weight is partly dependent on Piezo1 in osteoblast-lineage cells and TrkA signaling. [PDF]

Sci Rep
Hägg D, Li L, Beeve AT, Scheller EL, Bellman J, Anesten F, Zlatkovic J, Dalmau Gasull A, Font-Gironès F, Movérare-Skrtic S, Jansson JO, Ohlsson C.   +11 more
europepmc   +1 more source

MGM as a Large‐Scale Pretrained Foundation Model for Microbiome Analyses in Diverse Contexts

Advanced Science, EarlyView.
We present the Microbial General Model (MGM), a transformer‐based foundation model pretrained on over 260,000 microbiome samples. MGM learns contextualized microbial representations via self‐supervised language modeling, enabling robust transfer learning, cross‐regional generalization, keystone taxa discovery, and prompt‐guided generation of realistic,
Haohong Zhang, Yuli Zhang, Zixin Kang, Jiayun Xiong, Ronghua Yang, Kang Ning   +5 more
wiley   +1 more source

Genetic analysis of disqualifying traits in Nellore cattle. [PDF]

Trop Anim Health Prod
Salgado FR, Evangelista AF, Sesana JC, de Almeida Teixeira R, Dias LT.   +4 more
europepmc   +1 more source

Single‐Mitochondrion ATP Profiling Directs Discovery of Targetable OXPHOS Dependency in Cancers

Advanced Science, EarlyView.
MitoATP‐nFCM integrates nano‐flow cytometry with fluorogenic probes (ATP/membrane potential) and antibodies to quantify mitochondrial metabolites and protein expression at single‐organelle resolution, exposing oxidative phosphorylation (OXPHOS)‐driven metabolic rewiring in cancers.
Xu Xiao, Cheng Lu, Hao Chen, Jing Zhou, Yunyun Hu, Haonan Di, Guoqiang Su, Xiaomei Yan   +7 more
wiley   +1 more source

Whole-Genome Sequencing and Phenotypic Drug Susceptibility Testing of Bedaquilin, Delamanid, Pretomanid, and Linezolid in Drug-Resistant <i>Mycobacterium tuberculosis</i> from a Single Institute in South Korea. [PDF]

Pathogens
Choi HW, Kang YR, Son ES, Choi K, Cho M, Kim YJ, Lee SA, Lee JY, Kim JH, Kang SJ, Kee SJ, Lee JS, Lee HJ.   +12 more
europepmc   +1 more source

Anti‐Apoptotic and Neurite‐Protective Nanomedicine Augments Embryonic Stem Cells‐Derived Retinal Ganglion Cell Transplantation in Glaucoma Recovery

Advanced Science, EarlyView.
Lithium‐epigallocatechin gallate nanoparticles (Li‐EGCG NPs) are co‐transplanted with embryonic stem cell‐derived retinal ganglion cells (ESC‐RGCs) to enhance cell survival and therapeutic efficacy in an acute pathological glaucomatous injury model. This synergistic approach protects RGC cells, preserves retinal structure and improves visual function ...
Moxin Chen, Xiaoyan Jiang, Yuanhui Wang, Zhaobin Luo, Yu Zhang, Siwei Liu, Rui Huang, Dandan Zhang, Zhimin Tang, Yahan Ju, Shaohui Pan, Ni Ni, Wei Feng, Yu Chen, Ping Gu   +14 more
wiley   +1 more source

Genomic Characterization and Phylogenetic Analysis of <i>HA</i> and <i>NA</i> Genes of Influenza B Virus in Riyadh (2024-2025): Implications for Vaccine Strain Match. [PDF]

Viruses
Abdulgader SA, Aziz IM, Abdulwahed AM, Aljowaie RM, Farrag MA, Almuqrin AM, Alkubaisi NA, Almajhdi FN.   +7 more
europepmc   +1 more source