Results 181 to 190 of about 503,355 (348)

Genetic diversity and habitats of two enigmatic marine alveolate lineages [PDF]

open access: bronze, 2006
Agnès Groisillier   +4 more
openalex   +1 more source

New Perspectives on Semiconducting Conjugated Oligomers for Neuromodulation in Hydra vulgaris

open access: yesAdvanced Materials Interfaces, EarlyView.
Semiconducting organic compounds, thiophene‐based, modify the rhythmic electrical activity of the cnidarian Hydra vulgaris acting on specific neuronal circuits. The ETE‐S trimer also forms electronically conducting wires in the living tissues of the animal.
Giuseppina Tommasini   +7 more
wiley   +1 more source

Tuning the Morphological Properties of Granular Hydrogels to Control Lymphatic Capillary Formation

open access: yesAdvanced Materials Interfaces, EarlyView.
Tuning the morphological properties of granular hydrogels is essential to generate robust lymphatic capillary networks that express key lymphatic gene and protein markers. The study demonstrates that 3D in vitro lymphatic tube formation is controlled not by the mechanical properties of the gel, but by the pore size and topology (periodicity) of the gel
Daniel Montes   +7 more
wiley   +1 more source

Laser‐Induced Structuring of Biocompatible Polymers for the Controlled Orientation of Multinucleated Myotubes

open access: yesAdvanced Materials Interfaces, EarlyView.
Laser structuring of biocompatible polymers creates precise surface patterns that influence cell organization. By imaging, contact angle measurements, and chemical analysis, this study demonstrates the ability of laser‐induced micro‐structured surfaces to guide muscle cell alignment. These findings support laser patterning of biopolymers as a promising
Clarissa Murru   +7 more
wiley   +1 more source

Advances in Microfluidic Cochlea‐On‐A‐Chip

open access: yesAdvanced Science, EarlyView.
This review systematically examines diverse cell sources for inner ear organoids and outlines stepwise induction protocols. Furthermore, it discusses current applications and prospective developments of cochlea‐on‐a‐chip technologies in areas such as deafness modeling, mechanistic studies, and drug evaluation, with particular focus on gene‐therapy drug
Tian Shen   +10 more
wiley   +1 more source

Paracrine osteoprotegerin and β-catenin stabilization support synovial sarcomagenesis in periosteal cells [PDF]

open access: yes, 2017
Barrott, Jared J   +8 more
core   +2 more sources

Stereotyped Subclones Revealed by High‐Density Single‐Cell Lineage Tracing Support Robust Development

open access: yesAdvanced Science, EarlyView.
Based on a well‐established in vitro directed differentiation model and an integrated analysis of high‐density cell lineage trees (CLTs) and single‐cell transcriptomes, it is demonstrated that many subclones are formed by sub‐CLTs resembling each other in terms of both cell type compositions and topological structures.
Xiaoyu Zhang   +14 more
wiley   +1 more source

Exploring AAV‐Mediated Gene Therapy for Inner Ear Diseases: from Preclinical Success to Clinical Potential

open access: yesAdvanced Science, EarlyView.
Current preclinical studies of AAV‐mediated gene therapy explore different strategies based on the characteristics of inner ear diseases. For genetic hearing loss, approaches include the replacement of a “good gene,” removal of a “bad gene,” or direct correction of mutations through base editing.
Fan Wu   +7 more
wiley   +1 more source

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