Porcine reproductive and respiratory syndrome virus genotype 2 (PRRSV-2) genetic diversity in the U.S. was assessed using a database comprising 10 years’ worth of sequence data obtained from swine production systems routine monitoring and outbreak ...
Mariana Kikuti+5 more
doaj +2 more sources
Introduction: The population structure of Mycobacterium tuberculosis complex (MTBC) in Ethiopia is diverse but dominated by Euro-American (Lineage 4) and East-African-Indian (Lineage 3) lineages.
Mulualem Agonafir+8 more
doaj
Trypanosoma cruzi IIc: phylogenetic and phylogeographic insights from sequence and microsatellite analysis and potential impact on emergent Chagas disease. [PDF]
Trypanosoma cruzi, the etiological agent of Chagas disease, is highly genetically diverse. Numerous lines of evidence point to the existence of six stable genetic lineages or DTUs: TcI, TcIIa, TcIIb, TcIIc, TcIId, and TcIIe.
Acosta, Nidia+9 more
core +4 more sources
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi+3 more
wiley +1 more source
Kinship, lineage identity, and an evolutionary perspective on the structure of cooperative big game hunting groups in Indonesia. [PDF]
Work was conducted among traditional, subsistence whale hunters in Lamalera, Indonesia in order to test if kinship or lineage membership is more important for explaining the organization of cooperative hunting parties ranging in size from 8-14 men.
Alvard, Dr. Michael
core
Latent regulatory potential of human-specific repetitive elements [PDF]
At least half of the human genome is derived from repetitive elements, which are often lineage specific and silenced by a variety of genetic and epigenetic mechanisms. Using a transchromosomic mouse strain that transmits an almost complete single copy of
Barbosa-Morais, Nuno L.+15 more
core +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Rewiring the Drosophila Brain With Genetic Manipulations in Neural Lineages [PDF]
Neurons originate from neural stem cells and then synapse with stereotyped partners to form neuronal circuits. Recent findings indicate that several molecular mechanisms generating neuronal identity can rewire neuronal connectivity in the Drosophila brain when genetically manipulated.
openaire +3 more sources
Genetic and phenotypic characterization of Listeria monocytogenes lineage III [PDF]
Listeria monocytogeneshas been previously grouped into three evolutionary groups, termed lineages I, II and III. While lineages I and II are commonly isolated from various sources, lineage III isolates are rare and have several atypical and unique phenotypic characteristics.
Martin Wiedmann+5 more
openaire +3 more sources
Prevalence of \u3cem\u3eMyxobolus cerebralis\u3c/em\u3e Infections Among Genetic Lineages of \u3cem\u3eTubifex tubifex\u3c/em\u3e at Three Locations in the Madison River, Montana [PDF]
Host biodiversity can impact disease risk and influence the transmission of parasitic disease. Stream sediment–dwelling worms, Tubifex tubifex (Clitellata: Oligochaeta), are the definitive host of the parasite Myxobolus cerebralis (Myxozoa: Myxosporea ...
Kerans, Billie+2 more
core +1 more source