Results 81 to 90 of about 534,399 (300)

Cross-protection between antigenically distinct H1N1 swine influenza viruses from Europe and North America [PDF]

, 2011
Background An avian-like H1N1 swine influenza virus (SIV) is enzootic in swine populations of Western Europe. The virus is antigenically distinct from H1N1 SIVs in North America that have a classical swine virus-lineage H1 hemagglutinin, as does the ...
Brookes, Brown, Brown, Brown, Brownlee, Dürrwald, Garten, Grebe, Guan, Hinshaw, Hofshagen, Itoh, Kingsford, Kyriakis, Lange, Maurer-Stroh, Miller, Olsen, Olsen, Pensaert, Reed, Sandbulte, Scholtissek, Smith, Takemae, Van Reeth, Van Reeth, Van Reeth, Van Reeth, Van Reeth, Weingartl   +30 more
core   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Explaining microbial population genomics through phage predation [PDF]

, 2009
The remarkable diversity of genes within the pool of prokaryotic genomes belonging to the same species or pan-genome is difficult to reconcile with the widely accepted paradigm which asserts that periodic selection within bacterial populations would ...
Alex Mira, Ana-Belé, Beltrá, Forest Rohwer, Francisco Rodriguez-Valera, Lejla Pasic, T. Frede Thingstad   +6 more
core   +2 more sources

Genetic investigation within Lactococcus garvieae revealed two genomic lineages [PDF]

FEMS Microbiology Letters, 2012
The diversity of a collection of 49 Lactococcus garvieae strains, including isolates of dairy, fish, meat, vegetable and cereal origin, was explored using a molecular polyphasic approach comprising PCR-ribotyping, REP and RAPD-PCR analyses and a multilocus restriction typing (MLRT) carried out on six partial genes (atpA, tuf, dltA, als, gapC, and galP).
C. Ferrario, G. Ricci, F. Borgo, A. Rollando, M.G. Fortina   +4 more
openaire   +3 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Phylogeographic Structure Reveals Hidden Diversity Patterns in Tor tambra (Cyprinidae) Across Thai River Systems

Animals
Understanding patterns of genetic diversity and population structure in freshwater fishes is crucial for evolutionary studies and conservation planning.
Vatthanachai Phanklam, Sommai Janekitkarn, Kathathep Seesan, Narongrit Muangmai, Cong Zeng, Prapansak Srisapoome, Kornsorn Srikulnath, Ling Wu, Xiao-Yong Chen, Uthairat Na-Nakorn, Ishwar S. Parhar   +10 more
doaj   +1 more source

Lineages of the Cardiac Conduction System

Journal of Cardiovascular Development and Disease, 2017
The cardiac conduction system (CCS) initiates and coordinately propagates the electrical impulse to orchestrate the heartbeat. It consists of a set of interconnected components with shared properties.
Rajiv Mohan, Bas J. Boukens, Vincent M. Christoffels   +2 more
doaj   +1 more source

Shuffling of mobile genetic elements (MGEs) in successful healthcare-associated MRSA (HA-MRSA). [PDF]

, 2012
Methicillin-resistant Staphylococcus aureus (MRSA) CC22 SCCmecIV is a successful hospital-associated (HA-) MRSA, widespread throughout the world, and now the dominant clone in UK hospitals.
Budd, EL, Knight, GM, Lindsay, JA, McCarthy, AJ   +3 more
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Molecular epidemiology of Mycobacterium africanum in Ghana [PDF]

, 2016
BACKGROUND: Mycobacterium africanum comprises two phylogenetic lineages within the M. tuberculosis complex (MTBC) and is an important cause of human tuberculosis (TB) in West Africa. The reasons for this geographic restriction of M.
Ahorlu, Collins, Asante-Poku, Adwoa, Baddoo, Akosua, Bonsu, Frank, Borrell, Sonia, Forson, Audrey, Gagneux, Sebastien, Hattendorf, Jan, Koram, Kwadwo A., Laryea, Clement, Osei-Wusu, Stephen, Otchere, Isaac Darko, Sarpong, Esther, Yeboah-Manu, Dorothy   +13 more
core   +2 more sources