Results 71 to 80 of about 3,416,725 (336)

Genetic diversity of Mycobacterium tuberculosis isolates obtained from patients with pulmonary tuberculosis in Beira city, Mozambique

International Journal of Mycobacteriology, 2014
Background: Tuberculosis (TB) represents a serious public health problem in Mozambique, with an estimated incidence rate of 548 cases per 100,000 population in 2011.
Abuchahama Saifodine, Janet Fyfe, Aina Sievers, Elizabeth Coelho, Khalide Azam, James Black   +5 more
doaj   +1 more source

Effect of natural genetic variation on enhancer selection and function. [PDF]

, 2013
The mechanisms by which genetic variation affects transcription regulation and phenotypes at the nucleotide level are incompletely understood. Here we use natural genetic variation as an in vivo mutagenesis screen to assess the genome-wide effects of ...
Allison, KA, Benner, C, Glass, CK, Heinz, S, Kaikkonen, MU, Orozco, LD, Romanoski, CE   +6 more
core  

On the Bennelongia barangaroo lineage (Crustacea, Ostracoda) in Western Australia, with the description of seven new species [PDF]

, 2013
The ostracod genus Bennelongia De Deckker & McKenzie, 1981 is endemic to Australia and New Zealand. Extensive sampling in Western Australia (WA) revealed a high specific and largely undescribed diversity.
Halse, Stuart, Martens, Koen, Schön, Isa   +2 more
core   +4 more sources

Genetic diversity, seasonality and transmission network of human metapneumovirus: identification of a unique sub-lineage of the fusion and attachment genes

Scientific Reports, 2016
Human metapneumovirus (HMPV) is an important viral respiratory pathogen worldwide. Current knowledge regarding the genetic diversity, seasonality and transmission dynamics of HMPV among adults and children living in tropical climate remains limited. HMPV
Wei Zhen Chow, Y. Chan, X. Oong, Liang Jie Ng, S. Nor'e, K. T. Ng, Kok-Gan Chan, N. Hanafi, Y. Pang, A. Kamarulzaman, K. Tee   +10 more
semanticscholar   +1 more source

Protection of Omicron sub-lineage infection against reinfection with another Omicron sub-lineage

Nature Communications, 2022
There is significant genetic distance between SARS-CoV-2 Omicron (B.1.1.529) variant BA.1 and BA.2 sub-lineages. This study investigates immune protection of infection with one sub-lineage against reinfection with the other sub-lineage in Qatar during a ...
H. Chemaitelly, H. Ayoub, P. Coyle, P. Tang, H. Yassine, H. Al-Khatib, M. Smatti, M. Hasan, Z. Al-Kanaani, E. Al-Kuwari, A. Jeremijenko, A. Kaleeckal, A. Latif, R. M. Shaik, H. Abdul-Rahim, Gheyath K Nasrallah, M. G. Al-Kuwari, A. Butt, H. Al-Romaihi, M. Al-Thani, A. Al-Khal, R. Bertollini, L. Abu-Raddad   +22 more
semanticscholar   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

The role of landscape evolution in the genetic diversification of a stream fish Sarcocheilichthys parvus from Southern China

Frontiers in Genetics, 2023
Sarcocheilichthys parvus (Cypriniformes: Gobionidae) is a stream fish which is endemic to sub-tropical coastal drainages in southern China, thus offering a valuable model for understanding how genetic divergence arises in stream-adapting freshwater ...
Mingyue Li, Xishu Yang, Xiaomin Ni, Cuizhang Fu   +3 more
doaj   +1 more source

Chagas disease reactivation in a heart transplant patient infected by domestic Trypanosoma cruzi discrete typing unit I (TcIDOM) [PDF]

, 2015
Background Trypanosoma cruzi, causative agent of Chagas disease, displays high intraspecific genetic diversity: six genetic lineages or discrete typing units (DTUs) are currently recognized, termed TcI through TcVI.
Bhattacharyya, T., Burleigh, B.A., Costales, J.A., Garcia-Perez, J., Kotton, C.N., Llewellyn, M.S., Messenger, L.A., Zurita-Leal, A.C.   +7 more
core   +2 more sources

Pango lineage designation and assignment using SARS-CoV-2 spike gene nucleotide sequences

BMC Genomics, 2021
More than 2 million SARS-CoV-2 genome sequences have been generated and shared since the start of the COVID-19 pandemic and constitute a vital information source that informs outbreak control, disease surveillance, and public health policy.
Á. O'toole, O. Pybus, M. Abram, E. Kelly, A. Rambaut   +4 more
semanticscholar   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source