Results 241 to 250 of about 314,656 (291)

Diversification in the steppe rat snake <i>Elaphe dione</i> (Pallas, 1773) coincides with the Mid-Pleistocene climatic transition of Eurasia. [PDF]

PeerJ
Simonov E, Chernigova P, Lisachov A, Akhmedenov K, Ermakov O, Klenina A, Bakiev A, Nazarov R, Akhmedenova S, Jablonski D.   +9 more
europepmc   +1 more source

An Insulin‐Exosome‐TNFAIP8 Axis Drives Stromal Fibrosis and Therapeutic Resistance in Pancreatic Cancer

Advanced Science, EarlyView.
In pancreatic ductal adenocarcinoma (PDAC), insulin is associated with activation of PI3K/AKT–RAB3A signaling and enhanced secretion of TNFAIP8‐enriched exosomes from tumor cells. Uptake of these exosomes by fibroblasts is linked to TRIM21‐dependent STAT1 degradation and the emergence of myofibroblastic CAF–associated features, accompanied by increased
Zhenyu Li, Li Chen, Tao Wang, Haiyang Jiang, Huijuan Wang, Mengyu Li, Guanpeng Xie, Chunhua Xi, Han Yan, Chunhui Lu, Chenchen Li, Hanyu Zhu, Feihu Sun, Lingdi Yin, Jun Yu, Yi Miao   +15 more
wiley   +1 more source

A phosphoprotein gene RT-qPCR assay for detecting all lineages of peste des petits ruminants virus. [PDF]

Front Microbiol
Xu J, Zhao Y, Li H, Wang Q, Yu J, Wang Y, Bao J, Wang Z.   +7 more
europepmc   +1 more source

Embryonic cell lineage evolution in nematodes of clade IV and V

, 2006
openaire   +1 more source

TTNPB Promotes Human Pluripotent Stem Cell‐to‐Neural Stem Cell Transition via Modulation of Chromatin Accessibility and the S‐(5′‐adenosyl)‐L‐homocysteine/Choline Metabolic Network

Advanced Science, EarlyView.
A retinoic acid receptor agonist, TTNPB, drives the efficient generation of advanced neural stem cells (ANSCs) from human pluripotent stem cells. TTNPB‐centered chromatin remodeling and metabolic reprogramming, promote neuroectoderm commitment. The resulting cells show robust neural potential and functional efficacy in a rat depression model.
Ruilin Du, Yudi Ren, Qiaoqiao Meng, Peng Wei, Ruyu Zhu, Junjie Bao, Ye Yang, Shuo Yan, Chaorong Yue, Xueying Zhu, Shuo Cao, Chunxia Hao, Wei Sun, Yongli Song, Xihe Li, Zhimin Wu, Siqin Bao, Yanglin Chen   +17 more
wiley   +1 more source

A New Classification Framework to Understand Evolutionary Transitions in Individuality. [PDF]

Bioessays
Wilmsen S, Kost C.
europepmc   +1 more source

CRP Deficiency Rescues Periodontitis‐Induced Hippocampal Neurogenesis Impairment by Suppressing OPC‐Derived BMP4 Signaling in Rats

Advanced Science, EarlyView.
Chronic periodontitis elevates circulating CRP, which enters the hippocampus to upregulate BMP4 in oligodendrocyte precursor cells (OPCs), thereby impairing neurogenesis and inducing anxiety/depression‐like behaviors in rats. Counteracting this pathway, CRP deficiency helps confer functional resilience to OPCs.
Lingjie Li, Ping Deng, Siyu Hou, Xianbo Xia, Wei Zhao, Xingyu Zhu, Yang Zhang, Chao Wang, Ling Xu, Jinlin Song   +9 more
wiley   +1 more source

Comparative Genomic and Epidemiologic Analysis of Methicillin-Resistant <i>Staphylococcus aureus</i> Isolates in Republic of Korea. [PDF]

Antibiotics (Basel)
Kim DH, Han DG, Lee S, Yoo JS, Jeon SM.
europepmc   +1 more source

Investigation of avian louse flies as potential vectors of protozoan and bacterial pathogens of veterinary importance. [PDF]

Sci Rep
Keve G, Takács N, Csörgő T, Kováts D, Pitó A, Bende A, Németh Á, Benke A, Fenyvesi L, Lukács Z, Tamás EA, Mórocz A, Karcza Z, Keve G, Cutajar B, de Wulf E, Hornok S.   +16 more
europepmc   +1 more source

SERAPHIM 2.0: an extended toolbox for studying phylogenetically informed movements. [PDF]

Bioinformatics
Dellicour S, Faria NR, Rose R, Lemey P, Pybus OG.   +4 more
europepmc   +1 more source