Results 41 to 50 of about 107,950 (242)

Impact of target site distribution for Type I restriction enzymes on the evolution of methicillin-resistant Staphylococcus aureus (MRSA) populations. [PDF]

, 2013
A limited number of Methicillin-resistant Staphylococcus aureus (MRSA) clones are responsible for MRSA infections worldwide, and those of different lineages carry unique Type I restriction-modification (RM) variants.
Dryden, David T. F., White, John H., Stephanou, AS, Cooper, Laurie P., Cooper, LP, Houston, PJ, Lindsay, JA, Chen, K, Dryden, DT, Roberts, Gareth A., Lindsay, Jodi A., Chen, Kai, Roberts, GA, White, JH, Stephanou, Augoustinos S., Houston, Patrick J.   +15 more
core   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

'Incapable of Walking Without his Valido': the Privanza of the Pacheco Lineage (1435-1529)

, 2020
Starting off from a series of quotations taken from the Crónica de Enrique IV by fray Jerónimo de la Cruz (BNE, Mss. 1776), this article brings to light sources that justify why the first two Marquises of Villena – Juan Pacheco and Diego López Pacheco ...
Chicote Pompanin, María Teresa
core   +1 more source

Molecular Evolution of Peste des Petits Ruminants Virus

Emerging Infectious Diseases, 2014
Despite safe and efficacious vaccines against peste des petits ruminants virus (PPRV), this virus has emerged as the cause of a highly contagious disease with serious economic consequences for small ruminant agriculture across Asia, the Middle East, and ...
Murali Muniraju, Muhammad Munir, AravindhBabu R. Parthiban, Ashley Banyard, Jingyue Bao, Zhiliang Wang, Chrisostom Ayebazibwe, Gelagay Ayelet, Mehdi El Harrak, Mana Mahapatra, Geneviève Libeau, Carrie Batten, Satya Parida   +12 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

A distinct and divergent lineage of genomic island-associated Type IV Secretion Systems in Legionella. [PDF]

PLoS ONE, 2013
Legionella encodes multiple classes of Type IV Secretion Systems (T4SSs), including the Dot/Icm protein secretion system that is essential for intracellular multiplication in amoebal and human hosts. Other T4SSs not essential for virulence are thought to
Bryan A Wee, Megan Woolfit, Scott A Beatson, Nicola K Petty   +3 more
doaj   +1 more source

The Role of Lineage Plasticity in Prostate Cancer Therapy Resistance.

, 2019
Lineage plasticity has emerged as an important mechanism of treatment resistance in prostate cancer. Treatment-refractory prostate cancers are increasingly associated with loss of luminal prostate markers, and in many cases induction of developmental ...
Wicha, Max, Lotan, Tamara, Rubin, Mark A., Sears, Rosalie, Tawab-Amiri, Abdul, Dicker, Adam, Yu, Evan Y, Gulley, James L, Hildesheim, Jeffrey, Hecht, Toby, Thompson, Timothy, Goodrich, David W, Dahut, William, Sawyers, Charles L, Diaz Meco, Maria, Shen, Michael, Lin, Daniel, Nelson, Peter S, Scher, Howard I, Isaacs, Jennifer, Kelly, Kathleen, Zoubeidi, Amina, Rowley, David, Rudin, Charles M, Loda, Massimo, Knudsen, Karen, Beltran, Himisha, Hruszkewycz, Andrew, Arnold, Julia, White, Richard, Lee, John, Small, Eric J   +31 more
core   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Emergence and diversification of dengue 2 cosmopolitan genotype in Pakistan, 2011. [PDF]

PLoS ONE, 2013
Major dengue epidemics have been observed in the Indian subcontinent since the 1980s and have occurred with increased hospitalizations and mortality. In 2011, the first major epidemic of dengue occurred in Lahore, the second largest city in Pakistan, and
Mohammad A Khan, Esther M Ellis, Hasitha A Tissera, Mohammad Y Alvi, Fatima F Rahman, Faisal Masud, Angelia Chow, Shiqin Howe, Vijaykrishna Dhanasekaran, Brett R Ellis, Duane J Gubler   +10 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source