Results 91 to 100 of about 5,206,546 (317)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Linear Dependence Of Powers Of Linear Forms [PDF]

Annales Mathematicae Silesianae, 2015
Abstract The main goal of the paper is to examine the dimension of the vector space spanned by powers of linear forms. We also find a lower bound for the number of summands in the presentation of zero form as a sum of d-th powers of linear forms.
openaire   +4 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Generalized linear models [PDF]

, 1972
The technique of iterative weighted linear regression can be used to obtain maximum likelihood estimates of the parameters with observations distributed according to some exponential family and systematic effects that can be made linear by a suitable ...
Nelder, J. A., Wedderburn, R. W. M.
core   +1 more source

Deep learning-based localization algorithms on fluorescence human brain 3D reconstruction: a comparative study using stereology as a reference

Scientific Reports
3D reconstruction of human brain volumes at high resolution is now possible thanks to advancements in tissue clearing methods and fluorescence microscopy techniques.
Curzio Checcucci, Bridget Wicinski, Giacomo Mazzamuto, Marina Scardigli, Josephine Ramazzotti, Niamh Brady, Francesco S. Pavone, Patrick R. Hof, Irene Costantini, Paolo Frasconi   +9 more
doaj   +1 more source

Crystalline polymeric carbon dioxide stable at megabar pressures

Nature Communications, 2018
The nature and stability of carbon dioxide under extreme conditions relevant to the Earth’s mantle is still under debate, in view of its possible role within the deep carbon cycle.
Kamil F. Dziubek, Martin Ende, Demetrio Scelta, Roberto Bini, Mohamed Mezouar, Gaston Garbarino, Ronald Miletich   +6 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Sensorless Control of Permanent-Magnet Linear Synchronous Motor Based on Modified Linear Extended State Observer

, 2021
Permanent-Magnet Linear Synchronous Motor (PMLSM) transforms electric energy into linear mechanical kinetic energy without transmission mechanism which is widely used in rail transmit due to its merits of high efficiency, relatively low losses and simple
Xitong Niu, Yue Qu, Li, H, Lu, J, Qu, Y, Hui Li, Niu, X, Junwei Lu   +7 more
core   +1 more source

Quantitative cytoarchitectural phenotyping of deparaffinized human brain tissues

Communications Biology
Advanced 3D imaging techniques and image segmentation and classification methods can transform biomedical research by offering insights into the human brain cytoarchitecture under pathological conditions.
Danila Di Meo, Michele Sorelli, Josephine Ramazzotti, Franco Cheli, Samuel Bradley, Laura Perego, Beatrice Lorenzon, Giacomo Mazzamuto, Aron Emmi, Andrea Porzionato, Raffaele De Caro, Rita Garbelli, Dalila Biancheri, Cristiana Pelorosso, Valerio Conti, Renzo Guerrini, Francesco S. Pavone, Irene Costantini   +17 more
doaj   +1 more source