Results 101 to 110 of about 199,141 (285)

An Alvarez-Type Linac Configuration for Future Carbon and Helium Ion Therapy Facilities with Parallel Radioisotope Production

Instruments
The increasing demand for ion beams heavier than protons—particularly carbon and helium ions—for cancer therapy has driven the development of advanced accelerator technologies.
Lazar Nikitovic, Maurizio Vretenar, Toms Torims   +2 more
doaj   +1 more source

Jacobi equations and particle accelerator beam dynamics

, 2012
A geometric formulation of the linear beam dynamics in accelerator physics is presented. In particular, it is proved that the linear transverse and longitudinal dynamics can be interpret geometrically as an approximation to the Jacobi equation of an ...
Torrome, Ricardo Gallego
core  

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

XEM: Tensor accelerator for AB21 supercomputing artificial intelligence processor

ETRI Journal
As computing systems become increasingly larger, high-performance comput-ing (HPC) is gaining importance. In particular, as hyperscale artificial intelli-gence (AI) applications, such as large language models emerge, HPC has become important even in the ...
Won Jeon, Mi Young Lee, Joo Hyun Lee, Chun-Gi Lyuh   +3 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Heads of Sci-Tech Libraries

Issues in Science and Technology Librarianship, 1999
Pat Kreitz
doaj   +1 more source

Design of 200 MHz CW He2+ APF-DTLs for 211At production

Nuclear Engineering and Technology
Targeted Alpha-particle Therapy (TAT) has become a significant therapeutic way for cancer, as it can reduce relapsed refractory cancer. 211At is one of the most promising alpha-emitting radionuclides.
LiangZhou Yao, CanYu Wang, ZhengMao Zhang, Wei Ma, Liping Zou, Zhen Yang, Jinghe Yang, YuLin Ge, Liang Lu   +8 more
doaj   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source