Results 41 to 50 of about 7,284 (228)
Einstein Gravity, Lagrange-Finsler Geometry, and Nonsymmetric Metrics
We formulate an approach to the geometry of Riemann-Cartan spaces provided with nonholonomic distributions defined by generic off-diagonal and nonsymmetric metrics inducing effective nonlinear and affine connections.
Sergiu I. Vacaru
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Errors Dynamics in Affine Group Systems [PDF]
Errors dynamics captures the evolution of the state errors between two distinct trajectories, that are governed by the same system rule but initiated or perturbed differently.
Li, Xinghan +4 more
core +1 more source
The Ternary Structure of Lie Algebroid Connections [PDF]
We examine the heap of linear connections on anchored vector bundles and Lie algebroids. Naturally, this covers the example of affine connections on a manifold.
Andrew James Bruce, Bruce, Andrew James
core +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
A note on geodesic and almost geodesic mappings of homogeneous Riemannian manifolds [PDF]
Let \(M\) be a differentiable manifold and denote by \(\nabla\) and \(\tilde{\nabla}\) two linear connections on \(M\). \(\nabla\) and \(\tilde{\nabla}\) are said to be geodesically equivalent if and only if they have the same geodesics.
Stanisław Formella
doaj
Flat affine manifolds and their transformations
We give a characterization of flat affine connections on manifolds by means of a natural affine representation of the universal covering of the Lie group of diffeomorphisms preserving the connection.
Villabón Aldana, Edgar Andrés +2 more
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source

