Results 71 to 80 of about 8,035 (253)

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

open access: yesFEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Affine transformations of the tangent bundle with a complete lift connection over a manifold with a linear connection of special type

open access: yesДифференциальная геометрия многообразий фигур, 2018
In this paper we obtain exact upper bounds for the dimensions of Lie al­ge­bras of infinitesimal affine transformations in tangent bundles with a comp­lete lift connection in the case when the base space is a manifold equipped with a non-projective Euclidean linear connection of a special type.
A. Sultanov, G. Sultanova
openaire   +1 more source

On the universal connection of a system of connections

open access: yes, 1987
Given a system of connections on a fibred manifold, we study in detail the notion of universal connection and curvature.We compare different approaches and analyze the cases of linear, affine and principal bundles.
Cabras, Antonella
core   +1 more source

On Limit Sets for Geodesics of Meromorphic Connections

open access: yes, 2023
Meromorphic connections on Riemann surfaces originate and are closely related to the classical theory of linear ordinary differential equations with meromorphic coefficients.
Tahar, Guillaume   +2 more
core   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Algebraic theory of affine monoids

open access: yes, 2013
This thesis treats several aspects of affine monoids. First, we consider the structure of the set of holes of an affine monoid Q. This set is the difference between Q and its normalization.
Welker, Volkmar (Prof. Dr.)   +1 more
core   +1 more source

On the dimension of Lie algebrasof infinitesimal affine transformations of direct products of more than two spaces of affine connection of the first type

open access: yesDifferential Geometry of Manifolds of Figures
The theory of motions in generalized spaces is one of the directions in modern differential geometry. Such scientists as E. Cartan, P. K. Rashev­sky, P. A. Shirokov, I. P. Egorov, A.Ya. Sultanov and other scientists were engaged in the study of movements
M. V. Glebova, A. Sultanov
semanticscholar   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

Balanced generalized weighing matrices and their applications

open access: yesLe Matematiche, 2004
Balanced generalized weighing matrices include well-known classical combinatorial objects such as Hadamard matrices and conference matrices; moreover, particular classes of BGW -matrices are equivalent to certain relative difference sets.
Dieter Jungnickel, H. Kharaghani
doaj  

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