Results 81 to 90 of about 3,658,908 (303)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Linear discrepancy is Π2-hard to approximate
Information Processing Letters, 2021 In this note, we prove that the problem of computing the linear discrepancy of a given matrix is $Π_2$-hard, even to approximate within $9/8 - ε$ factor for any $ε> 0$. This strengthens the NP-hardness result of Li and Nikolov [ESA 2020] for the exact version of the problem, and answers a question posed by them.
openaire +3 more sources
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Two Mappings Related To Semi-Inner Products And Their Applications in Geometry of Normed Linear Spaces [PDF]
, 1998 In this paper we introduce two mappings associated with the lower and upper semiinner product (.,.)i and (.,.)s and with semi-inner products [.,.] (in the sense of Lumer) which generate the norm of a real normed linear space, and study properties of ...
Koliha, Jerry J, Dragomir, Sever S
core +4 more sources
Orbital: The Electronic Journal of Chemistry, 2014 The use of software in chemical calculations is a constant reality in both laboratories as well as in simulation processes of chemical transformations.
Diogenes Filho +1 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Finite Difference Approximation for Linear Stochastic Partial Differential Equations with Method of Lines [PDF]
A stochastic partial differential equation, or SPDE, describes the dynamics of a stochastic process defined on a space-time continuum. This paper provides a new method for solving SPDEs based on the method of lines (MOL).
McDonald, Stuart
core
Singular Perturbation Approximation for Linear Systems with Lévy Noise
, 2017 To solve a stochastic linear evolution equation numerically, finite dimensional approximations are commonly used. For a good approximation, one might end up with a sequence of ordinary stochastic linear equations of high order.
Redmann, M. +5 more
core +1 more source
Linear approximation of simple objects
Computational Geometry, 1992 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Jean-Marc Robert 0001 +1 more
openaire +3 more sources