Results 101 to 110 of about 5,134,174 (310)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Stanford Linear Accelerator Center Annual Environmental Monitoring Report, January--December 1989
, 1990 This progress report discusses environmental monitoring activities at the Stanford Linear Accelerator Center for 1989. Topics include climate, site geology, site water usage, land use, demography, unusual events or releases, radioactive and ...
Stanford Linear Accelerator Center
core +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
The code MINNLP, or Minnesota Linear Programming, is an interactive linear programming algorithm which is efficient in the use of computer storage space and computational time.
Fuller, Earl I.
core
Appendix 5: Bayesian linear model code
, 2015 R script containing code to run Bayesian linear model.
Clark, Robert G. +9 more
core +1 more source
IEEE Photonics Journal, 2017 In this paper, the performance of polar code in high-speed coherent optical orthogonal frequency division multiplexing (CO-OFDM) system with nonlinear and linear impairments is comprehensively investigated for the first time.
Ling Liu +5 more
doaj +1 more source
The Matroid of Supports of A Linear Code [PDF]
Applicable Algebra in Engineering, Communication and Computing, 1997 In this paper the author establishes relations between support weight distributions of a code and the Tutte polynomial of the corresponding matroid. This allows a simple proof of MacWilliams equation for support weight distributions.
openaire +3 more sources
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source