Results 111 to 120 of about 9,454,079 (375)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Performance Evaluation of High-Speed Polar Coded CO-OFDM System with Nonlinear and Linear Impairments

open access: yesIEEE Photonics Journal, 2017
In this paper, the performance of polar code in high-speed coherent optical orthogonal frequency division multiplexing (CO-OFDM) system with nonlinear and linear impairments is comprehensively investigated for the first time.
Ling Liu   +5 more
doaj   +1 more source

Linear-time general decoding algorithm for the surface code

open access: yes, 2018
A quantum error correcting protocol can be substantially improved by taking into account features of the physical noise process. We present an efficient decoder for the surface code which can account for general noise features, including coherences and ...
Darmawan, Andrew S., Poulin, David
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Regression Modeling Strategies with Applications to Linear Models, Logistic and Ordinal Regression and Survival Analysis (2nd Edition)

open access: yes, 2016
Regression Modeling Strategies is an advanced text, aimed at graduate students and re-searchers with a solid, comprehensive background in regression modeling. Readers should have a good working knowledge of regression analysis as well as R as all code is
James E. Helmreich
semanticscholar   +1 more source

Armadillo: a template-based C++ library for linear algebra

open access: yesJournal of Open Source Software, 2016
The C++ language is often used for implementing functionality that is performance and/or resource sensitive. While the standard C++ library provides many useful algorithms (such as sorting), in its current form it does not provide direct handling of ...
Conrad Sanderson, Ryan R. Curtin
semanticscholar   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Linear Codes Constructed from Two Weakly Regular Plateaued Functions with Index (p − 1)/2

open access: yesEntropy
Linear codes are the most important family of codes in cryptography and coding theory. Some codes only have a few weights and are widely used in many areas, such as authentication codes, secret sharing schemes and strongly regular graphs.
Shudi Yang, Tonghui Zhang, Zheng-an Yao
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

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