Results 121 to 130 of about 7,931,944 (349)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Performance analysis of unsourced multiple access technology encoding scheme

open access: yes物联网学报
Firstly, the existing unsourced multiple access coding schemes were introduced in two aspects: linear codes and compressed sensing codes. On this basis, two unsourced multiple access spread spectrum sequence detector schemes proposed by Pradhan and ...
MA Ding, BIAN Dongming, ZHANG Gengxin
doaj  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Gray images of the linear codes and their dual codes over F4+uF 4

open access: yesTongxin xuebao, 2012
The linear codes over ring F4+uF4 and field F4 were studied.By using the Gray weight wG ,the Gray distance dG of codes C over F4+uF4,and the Gray map ψ from (F4+uF4)n to F 4 2n ,the Gray image ψ(C)of linear codes C over F4+uF4 were ...
Xiu-sheng LIU, Hua-lu LIU
doaj   +2 more sources

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

A non-linear channel code for covert communications

open access: yes, 2019
This paper presents an explicit channel code design for covert communications in the Binary Symmetric Channel. The proposed architecture is composed of the serial concatenation of a linear code and a graph-based non-linear code baptized as moderate ...
Matas Navarro, David   +1 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Linear and Log-Linear Approximation

open access: yes
Linear and log-linear approximation, as detailed and used to compute the benchmark calibration in "Comparing solution methods for dynamic equilibrium economies".
Jesus Fernandez-Villaverde   +2 more
core  

Home - About - Disclaimer - Privacy