Results 71 to 80 of about 1,015,438 (326)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

LCD codes and LCP of codes from units of group rings

open access: yesSakarya Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 2019
A linear code with complementary dual(LCD) is a linear code such that LCD codes are of greatimportance due to their wide range of applications in consumer electronics,storage systems and cryptography. Group rings have a rich source of units. Alsothe well-
Mehmet Emin Köroğlu
doaj   +1 more source

Two Classes of Linear Codes From Weil Sums

open access: yesIEEE Access, 2020
In this article, we consider two classes of $p$ -ary linear codes. This article is a generalization of the recent construction methods given by Jian, Lin and Feng (2019).
Hong Lu, Shudi Yang
doaj   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

MODERATE-DENSITY BURST ERROR CORRECTING LINEAR CODES

open access: yesRatio Mathematica, 2003
Lower and upper bounds for the existence of linear codes which correct burst of length b (fixed) and whose weight lies between certain limits have been presented.
Bal Kishan Dass, Gangmei Sobha
doaj  

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

A linear construction for certain Kerdock and Preparata codes

open access: yes, 1993
The Nordstrom-Robinson, Kerdock, and (slightly modified) Pre\- parata codes are shown to be linear over $\ZZ_4$, the integers $\bmod~4$. The Kerdock and Preparata codes are duals over $\ZZ_4$, and the Nordstrom-Robinson code is self-dual. All these codes
A. R. Calderbank   +5 more
core   +1 more source

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