Results 51 to 60 of about 13,725 (250)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Operators commuting with complex symmetric weighted composition operators on H 2

open access: yesConcrete Operators
In this article, we initially study when an anti-linear Toeplitz operator is in the commutant of a composition operator. Primarily, we investigate weighted composition operators Wg,ψ{W}_{g,\psi } commuting with complex symmetric weighted composition ...
Bhuia Sudip Ranjan
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

THE REVIEW OF ALMOST PERIODIC SOLUTIONS TO A STOCHASTIC DIERENTIAL EQUATION [PDF]

open access: yesInternational Journal of Mathematical Modelling & Computations, 2016
This paper proves the existence and uniqueness of quadratic mean almost periodic mild so-lutions for a class of stochastic dierential equations in a real separable Hilbert space. Themain technique is based upon an appropriate composition theorem combined
Siavosh Ahmadi
doaj  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Dynamics of composition operators on weighted Banach Spaces of holomorphic functionsweighted Banach space

open access: yes四川大学学报. 自然科学版, 2017
In this paper, we discuss the disjoint hypercyclicity of linear composition on the weighted Banach spaces.Moreover,according to the difference of the analytic maps,we obtain a sufficient condition for the disjoint hypercyclicity and disjoint ...
HU Xiao-He
doaj  

Approximation by Overactivated and Spiked Convolutions as Positive Linear Operators

open access: yesMathematics
In this work, the author studied the quantitative approximation to the unit operator of three kinds of overactivated and spiked convolution type-operators.
George A. Anastassiou
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

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