Results 41 to 50 of about 77,454 (294)

Conjugate gradient acceleration of non-linear smoothing filters [PDF]

2015 IEEE Global Conference on Signal and Information Processing (GlobalSIP), 2015
The most efficient signal edge-preserving smoothing filters, e.g., for denoising, are non-linear. Thus, their acceleration is challenging and is often performed in practice by tuning filter parameters, such as by increasing the width of the local smoothing neighborhood, resulting in more aggressive smoothing of a single sweep at the cost of increased ...
Andrew Knyazev, Alexander Malyshev
openaire   +2 more sources

PK/PD modelling of comb-shaped PEGylated salmon calcitonin conjugates of differing molecular weights

, 2011
Salmon calcitonin (sCT) was conjugated via cysteine-1 to novel comb-shaped end-functionalised (poly(PEG) methyl ether methacrylate) (sCT-P) polymers, to yield conjugates of total molecular weights (MW) inclusive of sCT: 6.5, 9.5, 23 and 40 kDa.
Jesús M. Frías, David J. Brayden, Brayden, David J., Claire T. Sayers, Haddleton, David M., Ryan, Sinéad M., Sayers, Claire T., Wang, Xuexuan, Sinéad M. Ryan, David M. Haddleton, Xuexuan Wang, Frías, Jesús M., Brayden, David James   +12 more
core   +1 more source

Serological Benefit of SARS‐CoV‐2 Vaccination Relative to Infection in Children With Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with acute lymphoblastic leukemia (ALL) are at risk of severe outcomes from SARS‐CoV‐2 (SCV2). In the post‐pandemic context, where most children have been infected with SCV2, there are limited data on whether vaccination remains beneficial in children with ALL.
Janna R. Shapiro, Freda Qi, Karen Colwill, Alina D. Dorogy, Ying Liu, Michelle Science, Anne‐Claude Gingras, James M. Rini, Sumit Gupta, Sarah Alexander, Shelly Bolotin, Tania H. Watts   +11 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Identification of Metabolites of 6′-Hydroxy-3,4,5,2′,4′-pentamethoxychalcone in Rats by a Combination of Ultra-High-Performance Liquid Chromatography with Linear Ion Trap-Orbitrap Mass Spectrometry Based on Multiple Data Processing Techniques

Molecules, 2016
In this study, an efficient strategy was established using ultra-high-performance liquid chromatography coupled with linear ion trap-Orbitrap mass spectrometry (UHPLC-LTQ-Orbitrap MS) to profile the in vivo metabolic fate of 6′-hydroxy-3,4,5,2′,4 ...
Siyi Liu, Yanyun Che, Fei Wang, Zhanpeng Shang, Jianqiu Lu, Shengyun Dai, Jiayu Zhang, Wei Cai   +7 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Novel Multidrug-Resistant Enterococcal Mobile Linear Plasmid pELF1 Encoding vanA and vanM Gene Clusters From a Japanese Vancomycin-Resistant Enterococci Isolate

Frontiers in Microbiology, 2019
Vancomycin-resistant enterococci are troublesome pathogens in clinical settings because of few treatment options. A VanA/VanM-type vancomycin-resistant Enterococcus faecium clinical isolate was identified in Japan. This strain, named AA708, harbored five
Yusuke Hashimoto, Makoto Taniguchi, Kazuma Uesaka, Takahiro Nomura, Hidetada Hirakawa, Koichi Tanimoto, Kiyoko Tamai, Genjie Ruan, Bo Zheng, Haruyoshi Tomita, Haruyoshi Tomita   +10 more
doaj   +1 more source

Low efficiency of homology-facilitated illegitimate recombination during conjugation in Escherichia coli. [PDF]

PLoS ONE, 2011
Homology-facilitated illegitimate recombination has been described in three naturally competent bacterial species. It permits integration of small linear DNA molecules into the chromosome by homologous recombination at one end of the linear DNA substrate,
Jihane Amarir-Bouhram, Mélodie Goin, Marie-Agnès Petit   +2 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Linear computation of unbordered conjugate on unordered alphabet

Theoretical Computer Science, 2014
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Jean-Pierre Duval, Thierry Lecroq, Arnaud Lefebvre   +2 more
openaire   +2 more sources