Results 61 to 70 of about 77,454 (294)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Effect of a ring on the cyclic conjugation in another ring: applications to acenaphthylene-type polycyclic conjugated molecules [PDF]

Journal of the Serbian Chemical Society, 2010
In a recent work, a method was developed for assessing the influence ief(G, Z0|Z1) of a ring Z1 on the energy effect of another ring Z0 in a polycyclic conjugated molecule G. Herein, a report is given of detailed numerical investigations of ief(G, Z0|Z1)
SLAVKO RADENKOVIĆ, SVETLANA JEREMIĆ, IVAN GUTMAN, BORIS FURTULA   +3 more
doaj  

On Feller semigroup generated by solution of nonlocal parabolic conjugation problem

Karpatsʹkì Matematičnì Publìkacìï, 2018
The paper deals with the problem of construction of Feller semigroup for one-dimensional inhomogeneous diffusion processes with membrane placed at a point whose position on the real line is determined by a given function that depends on the time variable.
B.I. Kopytko, R.V. Shevchuk
doaj   +1 more source

Isolipoic acid-linked gold nanoparticles bearing the thomsen friedenreich tumor-associated carbohydrate antigen: Stability and in vitro studies

Frontiers in Chemistry, 2022
We have previously prepared gold nanoparticles (AuNPs) bearing the Thomsen-Friedenreich antigen disaccharide (TFag), a pan-carcinoma, Tumor-Associated Carbohydrate Antigen (TACA), as tools for various assays and biological applications.
Utpal K. Mondal, Joseph J. Barchi
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Synthesis and Structure-Activity Relationships of Amino Acid Conjugates of Cholanic Acid as Antagonists of the EphA2 Receptor

Molecules, 2013
The Eph–ephrin system plays a critical role in tumor growth and vascular functions during carcinogenesis. We had previously identified cholanic acid as a competitive and reversible EphA2 antagonist able to disrupt EphA2-ephrinA1 interaction and to ...
Alessio Lodola, Silvia Rivara, Elisabetta Barocelli, Francesca De Franco, Paola Vicini, Antimo Gioiello, Carmine Giorgio, Iftiin Hassan-Mohamed, Riccardo Castelli, Daniele Pala, Matteo Incerti, Marco Mor, Massimiliano Tognolini, Simonetta Russo   +13 more
doaj   +1 more source

Nonlocal solitons supported by non-parity-time-symmetric complex potentials

New Journal of Physics, 2020
We report on the existence and stability of fundamental and out-of-phase dipole solitons in nonlocal focusing Kerr media supported by one-dimensional non-parity-time (PT)-symmetric complex potentials.
Xing Zhu, Xi Peng, Yunli Qiu, Hongcheng Wang, Yingji He   +4 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Maxillofacial morphological factors related to acceleration of maxillary growth attributed to facial mask treatment: a structural superimposition study

Progress in Orthodontics, 2019
Background Anatomical textbooks mention that the contact between the pterygoid process and the palatine’s pyramidal process is not a “suture” but “conjugation.”.The aim was to evaluate the maxillofacial morphological factor responding most to the ...
Takashi S. Kajii, Yui Sakaguchi, Yoshihiko Sawa, Sachio Tamaoki   +3 more
doaj   +1 more source