Results 181 to 190 of about 3,440,903 (289)
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
A Design of VSS for a Linear System with Bounded Control
Kazunobu YOSHIDA, Hisashi Kawabe
openalex +2 more sources
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Autoencoders decode polyunsaturated fatty acid metabolism with strong genetic architecture in cancer risk. [PDF]
Liu W, Gao H, Qian K.
europepmc +1 more source
Micrometer Backstepping Control System for Linear Motion Single Axis Robot Machine Drive [PDF]
Chih‐Hong Lin, Kuo‐Tsai Chang
openalex +1 more source
PARAMETRIC EVALUATION ON A COMPUTER OF THE QUALITY OF LINEAR AUTOMATIC CONTROL SYSTEMS
А. Grushun, T. Grushun
openalex +2 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Non-linear model predictive control for variable speed hydropower. [PDF]
Nepal T +5 more
europepmc +1 more source

