Results 61 to 70 of about 3,330,411 (337)
ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling
FEBS Letters, EarlyView.In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li +3 more
wiley +1 more source
Controllability of Continuous Bimodal Linear Systems [PDF]
Mathematical Problems in Engineering, 2013 We consider bimodal linear systems consisting of two linear dynamics acting on each side of a given hyperplane, assuming continuity along the separating hyperplane. We prove that the study of controllability can be reduced to the unobservable case, and for these ones we obtain a simple explicit characterization of controllability for dimensions 2 and 3,
Ferrer Llop, Josep +2 more
openaire +3 more sources
FEBS Letters, EarlyView.Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield +3 more
wiley +1 more source
Natural Factorization of Linear Control Systems through Parallel Gathering of Simple Systems
Journal of Mathematics, 2023 Linear systems over vector spaces and feedback morphisms form an additive category taking into account the parallel gathering of linear systems. This additive category has a minimal exact structure and thus a notion of simple systems as those systems ...
M. V. Carriegos
doaj +1 more source
Controllability of a Linear System With Nonnegative Sparse Controls [PDF]
IEEE Transactions on Automatic Control, 2022 This paper studies controllability of a discrete-time linear dynamical system using nonnegative and sparse inputs. These constraints on the control input arise naturally in many real-life systems where the external influence on the system is unidirectional, and activating each input node adds to the cost of control.
openaire +2 more sources
Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells
FEBS Letters, EarlyView.Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan +2 more
wiley +1 more source
FEBS Letters, EarlyView.C‐mannosylation is a unique form of protein glycosylation. In this study, we demonstrated that ADAMTS1 is C‐mannosylated at Trp562 and Trp565 in human testicular germ cell tumor NEC8 cells. We found that C‐mannosylation of ADAMTS1 is essential for its secretion, processing, enzymatic activity, and ability to promote vasculogenic mimicry. These findings
Takato Kobayashi +5 more
wiley +1 more source
H∞ positive filter-based control for positive linear systems [PDF]
Archives of Control SciencesThis paper deals with the design of a positive functional H∞ filter-based controller for positive linear systems subject to bounded energy disturbances. We propose a new approach to numerically compute the controller, which is obtained via a function of ...
Montassar Ezzine +3 more
doaj +1 more source
Modelling and simulation of advanced non-linear autopilot designs [PDF]
, 2010 This paper presents the simulation in ESL of a non-linear 6 degree-of-freedom missile model with an advanced, non-linear, multivariable autopilot designed using Rate Actuated Inverse Dynamics (RAID) methods. High performance control of non-linear systems
Brindley, Joseph +2 more
core
FEBS Letters, EarlyView.The Arabidopsis mutants hls1 hlh1 and amp1 lamp1 exhibit pleiotropic developmental phenotypes. Although the functions of the causative genes remain unclear, they act in the same genetic pathway and are thought to generate non‐cell‐autonomous signals.
Takashi Nobusawa, Makoto Kusaba
wiley +1 more source