Results 71 to 80 of about 2,136,673 (353)

Numerical integration of the boundary value problems for the second order nonlinear ordinary differential equations of an arbitrary structure using an iterative procedure

open access: yesVestnik Samarskogo Gosudarstvennogo Tehničeskogo Universiteta. Seriâ: Fiziko-Matematičeskie Nauki, 2016
An iterative procedure for numerical integration of boundary-value problems for nonlinear ordinary differential equations of the second order of arbitrary structure is suggested.
Vladimir N Maklakov
doaj   +1 more source

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Reproducing Kernel Space Method for the Solution of Linear Fredholm Integro-Differential Equations and Analysis of Stability

open access: yesAbstract and Applied Analysis, 2012
We present a numerical method to solve the linear Fredholm integro-differential equation in reproducing kernel space. A simple algorithm is given to obtain the approximate solutions of the equation. Through the comparison of approximate and true solution,
Xueqin Lv, Yue Gao
doaj   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Oscillation of Half-Linear Differential Equations with Delay

open access: yesAbstract and Applied Analysis, 2013
We study the half-linear delay differential equation , , We establish a new a priori bound for the nonoscillatory solution of this equation and utilize this bound to derive new oscillation criteria for this equation in terms of oscillation criteria for ...
Simona Fišnarová, Robert Mařík
doaj   +1 more source

A New Analytical Procedure for Solving the Non-Linear Differential Equation Arising in the Stretching Sheet Problem

open access: yesInternational Journal of Applied Mechanics and Engineering, 2013
The paper discusses a new analytical procedure for solving the non-linear boundary layer equation arising in a linear stretching sheet problem involving a Newtonian/non-Newtonian liquid. On using a technique akin to perturbation the problem gives rise to
P.G. Siddheshwar   +2 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Localization of the eigenvalues of linear integral equations with applications to linear ordinary differential equations [PDF]

open access: yes
Localization of linear integral equation eigenvalues with applications to linear ordinary differential ...
Kranzler, S. K., Sloss, J. M.
core   +1 more source

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