Results 91 to 100 of about 279,382 (273)

Bifidobacterium Pseudolongum‐Derived Acetate Attenuates Acute Pancreatitis Through GPR43‐Mediated Suppression of M1 Macrophage Polarization

Advanced Science, EarlyView.
The severity of acute pancreatitis (AP) is linked to reduced abundance of Bifidobacterium pseudolongum (B. pseudolongum). Administration of B. pseudolongum or its key metabolite acetate alleviates pancreatic and systemic inflammation by suppressing M1 macrophage polarization.
Langyi Guan, Xueyang Li, Cong He, Pan Zheng, Yaoyu Zou, Qi Zhu, Xin Li, Jie Liang, Junmin Yang, Li Zhang, Yuman Ye, Jianhua Wan, Huajing Ke, Jianping Liu, Nonghua Lu, Nianshuang Li, Yin Zhu   +16 more
wiley   +1 more source

Multicohort Validation of Gut Microbiome Signatures for Cholangiocarcinoma Diagnosis and Functional Characterization of Bifidobacterium Pseudocatenulatum

Advanced Science, EarlyView.
This study analyzes gut bacteria in cholangiocarcinoma patients, revealing distinct microbial signatures that enable accurate disease detection. Species‐based diagnostic models achieved over 98% accuracy in identifying cholangiocarcinoma and distinguished it from other liver diseases. The research demonstrates that specific beneficial bacteria suppress
Benchen Rao, Jianwen Jiang, Ruiqing Zhang, Dongya Zhang, Chenchen Zhang, Ang Li, Haifeng Lu, Hua Zhang, Lin Zhou, Wenzhi Guo, Peihao Wen, Jianfeng Xue, Jie Pan, Tuerganaili Aji, Zhou Lan, Xianzhi Jiang, Shusen Zheng, Zujiang Yu, Zhigang Ren   +18 more
wiley   +1 more source

Long‐Tea‐CLIP: An Expert‐Level Multimodal AI Framework for Fine‐Grained Green Tea Grading Across Five Sensory Dimensions

Advanced Science, EarlyView.
Long‐Tea‐CLIP (Contrastive Language‐Image Pre‐training) presents a multimodal AI framework that integrates visual, metabolomic, and sensory knowledge to grade green tea across appearance, soup color, aroma, taste, and infused leaf. By combining expert‐guided modeling with CLIP‐supervised learning, the system delivers fine‐grained quality evaluation and
Yanqun Xu, Zhengfang Xue, Qing Luo, Xu Liu, Yongquan Xu, Huang Jing, Xingcai Zhang, Xinyuan Zhang, Zhonghua Liu, Zisheng Luo   +9 more
wiley   +1 more source

A Multi Linear Discriminant Analysis Method Using a Subtraction Criteria

پژوهش‌های ریاضی, 2017
Linear dimension reduction has been used in different application such as image processing and pattern recognition. All these data folds the original data to vectors and project them to an small dimensions.
m rezghi, amin rastegar
doaj  

Communications inspired linear discriminant analysis [PDF]

We study the problem of supervised linear dimensionality reduction, taking an information-theoretic viewpoint. The linear projection matrix is designed by maximizing the mutual information between the projected signal and the class label. By harnessing a
Calderbank, R, Carin, L, Carson, W, Chen, M, Rodrigues, M   +4 more
core  

ROBUSTNESS OF LINEAR DISCRIMINANT ANALYSIS

JOURNAL OF THE JAPAN STATISTICAL SOCIETY, 1998
Summary: This paper investigates the robustness properties of linear discriminant analysis. We study the problem distorting the assumptions of the linear discriminant rule that the populations are normally distributed and they have equal variance and covariance matrices.
openaire   +3 more sources

Bifidobacterium Breve Yang08 Alleviates Atopic Dermatitis By Enriching Akkermansia Muciniphila and Inhibiting Neutrophil Extracellular Traps Formation In Mice

Advanced Science, EarlyView.
A novel Bifidobacterium breve strain, Yang08, is isolated to counter its depletion in atopic dermatitis. In mice, live Yang08 requires an intact gut microbiota to exert protection, specifically enriching Akkermansia muciniphila and potently inhibiting pathogenic neutrophil activation and NETosis in the skin.
Yanqiang Shi, Shuang He, Chengyi Li, Hung Chan, Zhenfeng Liu, Bin Yang, Qing Li   +6 more
wiley   +1 more source

SMAD4 Palmitoylation Drives a Metabolic‐Transcriptional Circuit to Promote Tumorigenesis and Confers Radiosensitivity in Pancreatic Cancer

Advanced Science, EarlyView.
This study identifies palmitoylation as a novel regulatory modification of SMAD4, mediated by ZDHHC22/APT2. It activates fatty acid synthesis, creating a self‐reinforcing SMAD4–FASN–palmitate feedback loop that drives pancreatic cancer growth and enhances radiotherapy sensitivity.
Yang Wang, Shan Zhang, Junping Bai, Xiaobing Li, Yi Han, Min Ji, Chongyi Jiang, Xiaobei Ge, Tianyu Yu, Yongying Hou, Jun Zhang, Wangting Li, Yiran Song, Jiaying Cai, Yingqun Zhou, Liwei An, Feng Wang   +16 more
wiley   +1 more source

Endogenous Ceramide 24:1 Constrains Th17‐Driven Neutrophilic Inflammation by Antagonizing EP2 Signaling

Advanced Science, EarlyView.
Cer24:1 levels are reduced in neutrophilic asthma and inversely correlate with disease severity and airway neutrophilia. Restoring Cer24:1 suppresses pathogenic Th17 differentiation by engaging EP2 on CD4+ T cells, thereby dampening the JAK2–STAT3–RORγt axis and reducing IL‐17 production.
Huan Liu, Abudureyimujiang Aili, Zheng Kuang, Liting Cao, Zemin Li, Ying Shang, Yingying Ge, Tingting Hu, Yongchang Sun, Wuli Zhao, Rong Jin, Chun Chang   +11 more
wiley   +1 more source

ON THE CONSISTENCY AND ROBUSTNESS PROPERTIES OF LINEAR DISCRIMINANT ANALYSIS [PDF]

Strong consistency of linear discriminant analysis is established under wide assumptions on the class conditional densities. Robustness to the presence of a mild degree of class dispersion heterogeneity is also analyzed.
Adolfo Hemández, Santiago Velilla
core