Results 91 to 100 of about 111,184 (298)

Bifidobacterium Pseudolongum‐Derived Inosine Mitigates Polystyrene Nanoplastics‐Induced Hepatic Injury by Inhibiting the Polarization of M1 Macrophages

Advanced Science, EarlyView.
Probiotic B.p colonization elevated gut‐derived inosine level in the liver, while elevated inosine activated A2AR and subsequently blocked NPs‐induced polarization of M1 macrophages by repressing the miR155/SOCS1/NF‐κB pathway. This reduced the release of inflammatory cytokines and thereby, mitigated NPs‐induced hepatic injury.
Kaikai Zhang, Yuchuan Chen, Jiayuan Wan, Jianzheng Yang, Lijian Chen, Qingyuan Li, Anding Zhou, Nian Zhou, Jiuyang Ding, Qi Wang, Jian Sun   +10 more
wiley   +1 more source

PENGENALAN WAJAH MENGGUNAKAN METODE LINEAR DISCRIMINANT ANALYSIS DAN K NEAREST NEIGHBOR

Jurnal Informatika, 2017
Pengenalan wajah merupakan sistem biometrika yang banyak digunakan untuk pengenalan individu pada penggunaan mesin absensi atau akses kontrol. Hal ini karena wajah merupakan salah satu ciri biometrika yang paling umum digunakan untuk mengenali seseorang.
Fandiansyah Fandiansyah, Jayanti Yusmah Sari, Ika Purwanti Ningrum   +2 more
doaj   +1 more source

Over-optimism in bioinformatics: an illustration [PDF]

, 2010
In statistical bioinformatics research, different optimization mechanisms potentially lead to "over-optimism" in published papers. The present empirical study illustrates these mechanisms through a concrete example from an active research field.
Arthur, Tenenhaus, Arthur Tenenhaus, Strimmer, Korbinian, Strimmer, K., Boulesteix, Anne-Laure, Monika, Jelizarow, Vincent Guillemot, Vincent, Guillemot, Tenenhaus, Arthur, Anne-Laure Boulesteix, Guillemot, Vincent, Monika Jelizarow, Jelizarow, Monika, Korbinian Strimmer, Anne-Laure, Boulesteix, Korbinian, Strimmer   +15 more
core   +1 more source

Astrocytic Phenotypic Switching in Posterior Piriform Cortex Orchestrates Bone Cancer Pain–Depression Comorbidity via Purinergic–Noradrenergic Signaling

Advanced Science, EarlyView.
Bone cancer pain and depression share a common origin: astrocytic A2‐to‐A1 transition in the posterior piriform cortex. This phenotypic shift disrupts the ATP–adenosine–A2AR–norepinephrine axis, simultaneously driving nociceptive and affective dysfunction.
Jiang‐Ping Liu, Jun‐Han Zhang, Zhi‐Xuan Tan, Wei‐Bing Yan, Ya‐Ru Yuan, Yao Liu, Bing‐Di Wei, Meng‐Qi Ding, Zhuo‐Min Fu, Ying Liu, An‐Qi Wang, Lin Ma, Yong‐Hong Li, Er‐Qing Chai, Chao‐Jun Wei   +14 more
wiley   +1 more source

Leveraging Linear Discriminant Analysis for Early Mental Health Disorder Identification

JRST: Jurnal Riset Sains dan Teknologi
Mental health disorders pose a significant global challenge, with early identification playing a crucial role in effective intervention and treatment.
Deden Iwan Setiawan, Marselina Endah Hiswati, Sriwidodo Sriwidodo, Mohammad Diqi, Luh Putu Erikawati, Rahayu Cahya Ariani   +5 more
doaj   +1 more source

Regularized Deep Linear Discriminant Analysis [PDF]

, 2022
As a non-linear extension of the classic Linear Discriminant Analysis(LDA), Deep Linear Discriminant Analysis(DLDA) replaces the original Categorical Cross Entropy(CCE) loss function with eigenvalue-based loss function to make a deep neural network(DNN ...
Lu, Wen
core   +1 more source

Cotton Recruits Soil‐Derived Delftia tsuruhatensis to Suppress Aphid Detoxification Via Salicylic Acid‐Mediated Defense

Advanced Science, EarlyView.
This study systematically reveals a complex interactive network involving plants, microbes, and insects, elucidating the ecological and molecular mechanisms by which cotton enhances its resistance to aphids through the active recruitment of the beneficial soil bacterium Delftia tsuruhatensis.
Hui Xue, Fengchao Diao, Qiqing Yu, Xiangzhen Zhu, Tingfang Zhong, Li Wang, Kaixin Zhang, Dongyang Li, Jichao Ji, Junyu Luo, Jinjie Cui, Xueke Gao   +11 more
wiley   +1 more source

Dimension-adaptive bounds on compressive FLD Classification [PDF]

, 2013
Efficient dimensionality reduction by random projections (RP) gains popularity, hence the learning guarantees achievable in RP spaces are of great interest.
Kabán, Ata, Robert J. Durrant, Ata Kabán, Durrant, Robert J.   +3 more
core   +1 more source

Intestinal Source Control of Lipid Metabolism by Enzyme‐Probiotic Encapsulated, Spatiotemporal Crosslinked, and Small Intestine‐Adhesive Hydrogel Microspheres

Advanced Science, EarlyView.
A thiol‐modified alginate hydrogel microsphere‐encapsulated enzyme‐probiotic biohybrid (AKK‐COD) system has been developed to address the spatiotemporal delivery and colonization challenges of small intestine‐targeted probiotic for lipid metabolism regulation. The system exerts sequential functions of intragastric protection, small intestinal adhesion,
Xiaolin Wu, Weiwen Liang, Siqi He, Guangyuan Chen, Hui Zhou, Xinglong Wang, Yifei Li, Dingcai Wu, Bingna Zheng, Ruoxu Dou, Rongkang Huang   +10 more
wiley   +1 more source

Dimension Reduction in Nonparametric Discriminant Analysis [PDF]

A dimension reduction method in kernel discriminant analysis is presented, based on the concept of dimension reduction subspace. Examples of application are discussed.
Santiago Velilla, Adolfo Hernández
core