Results 71 to 80 of about 17,388 (283)

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Non-linear discrete-time observer design by sliding mode

open access: yes, 2007
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University, 09/02/2007.Research into observer design for non-linear discrete-time systems has produced many design methods.
Algarawi, Mohammed
core  

Satellites Autonomous Navigation With an Extended State and Disturbance Sliding Mode Observer Method

open access: yesIEEE Access, 2019
This paper considers the satellites autonomous navigation problem with an extended sliding mode observer method. First, on consideration that the relative dynamic equation of chaser and target spacecrafts refers to a nonlinear time-varying system, a ...
Hang Yi, Ming Liu, Huayi Li
doaj   +1 more source

Feedback Linearization Kalman Observer Based Sliding Mode Control for Semi-Active Suspension Systems

open access: yesIEEE Access, 2020
In this paper, a new approach for an observer based controller for semi-active suspension systems is presented. The observer part is a feedback linearization Kalman filter which is based on differential geometry.
Zheng Liu   +4 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Reciprocal Neural State–Disturbance Observer for Model-Free Trajectory Tracking of Robotic Manipulators

open access: yesMathematics
High-precision trajectory tracking of robotic manipulators is fundamentally challenged by strong nonlinear dynamics, unmodeled uncertainties, and external disturbances.
Binluan Wang   +3 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Discrete time fast sliding-mode control for permanent magnet linear motor with nonlinear extended state observer

open access: yes, 2019
In this paper, a nonlinear extended state observer (NLESO)-based discrete-time fast terminal sliding mode controller (FTSMC) is proposed for the high-precision position tracking of permanent magnet linear motor.
Youhao Hu, Hu, Y., Wang, H., Hai Wang
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

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