Results 71 to 80 of about 17,388 (283)
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Non-linear discrete-time observer design by sliding mode
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University, 09/02/2007.Research into observer design for non-linear discrete-time systems has produced many design methods.
Algarawi, Mohammed
core
Satellites Autonomous Navigation With an Extended State and Disturbance Sliding Mode Observer Method
This paper considers the satellites autonomous navigation problem with an extended sliding mode observer method. First, on consideration that the relative dynamic equation of chaser and target spacecrafts refers to a nonlinear time-varying system, a ...
Hang Yi, Ming Liu, Huayi Li
doaj +1 more source
Feedback Linearization Kalman Observer Based Sliding Mode Control for Semi-Active Suspension Systems
In this paper, a new approach for an observer based controller for semi-active suspension systems is presented. The observer part is a feedback linearization Kalman filter which is based on differential geometry.
Zheng Liu +4 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
High-precision trajectory tracking of robotic manipulators is fundamentally challenged by strong nonlinear dynamics, unmodeled uncertainties, and external disturbances.
Binluan Wang +3 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
In this paper, a nonlinear extended state observer (NLESO)-based discrete-time fast terminal sliding mode controller (FTSMC) is proposed for the high-precision position tracking of permanent magnet linear motor.
Youhao Hu, Hu, Y., Wang, H., Hai Wang
core +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source

