Results 31 to 40 of about 1,129 (248)

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Using permutation function and the Bank of LFSR's in pseudo random generator keys

Tikrit Journal of Pure Science, 2023
In this paper a Bank of Linear Feedback Shift Registers (LFSR) is used to design and build a system for cryptography. This algorithm consists of 16 Linear Feedback Shift Registers.
Ali Khalil Salih
doaj   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Linear feedback shift registers and the minimal realization problem [PDF]

, 2019
[EN] The Berlekamp-Massey algorithm solves the problem of finding the shortest linear feedback shift register which generates a given finite sequence of scalars.
Roca Martinez, Alicia, Baragana, Itziar, Itziar Baragaña, Alicia Roca   +3 more
core   +1 more source

Power analyzer of linear feedback shift register techniques using built in self test

, 2022
Wasteful patterns that don't lead to fault dropping squander a tone of energy in the linear-feedback shift register and circuit under examination in a random research region. Random switching actions in the CUT and scan pathways between applications with
Ramalingam, Nagarajan, Sathish Sivaraman, Venusamy, Kanagaraj, Kanagaraj Venusamy, Kannadhasan Suriyan, Manjunathan Alagarsamy, Suriyan, Kannadhasan, Nagarajan Ramalingam, Balasubramaniyan, Kiruthiga, Kiruthiga Balasubramaniyan, Sivaraman, Sathish, Alagarsamy, Manjunathan   +11 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Construction de Bruijn sequence based on whole LFSR with 4 cycles

Tongxin xuebao, 2022
In order to improve the construction efficiency and widen the application depth of cycle-joining method, from the view of the number of cycles in the cycle structure, a method for constructing de Bruijn sequence based on whole LFSR with 4 cycles was ...
Congwei ZHOU, Bin HU, Jie GUAN
doaj   +2 more sources

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Fault-tolerant quantum-dot cellular automata linear feedback shift register for nano communication applications

Results in Optics
There has been remarkable research carried out on Nano-electronics where Quantum dot Cellular automata appearing as the next generation computing regimes.
Birinderjit Singh Kalyan, Balwinder Singh   +1 more
doaj   +1 more source