Results 41 to 50 of about 7,365 (273)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

On the number of linear forms in logarithms

Journal of Number Theory, 2007
8 ...
openaire   +2 more sources

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Formas lineares em logaritmos p-ádicos aplicadas na resolução de equações diofantinas [PDF]

, 2016
Dissertação (mestrado)—Universidade de Brasília, Departamento de Matemática, Programa de Pós-Graduação em Matemática, 2016.Esta dissertação trata das formas lineares em logaritmos p-ádicos.
Kreutz, Alesssandra
core   +1 more source

GUARANTEED PREDICTIVE ESTIMATION OF SOLUTIONS OF SYSTEMS OF DIFFERENTIAL EQUATIONS WITH THE GOMPERTZIAN DYNAMICS WITH OBSERVATIONS IN DISCRETE TIME MOMENTS

Міжнародний науково-технічний журнал "Проблеми керування та інформатики"
In this paper, we introduce a mathematical model of spreading information messages. Suppose, a community is influenced by one of n sources of information.
О.Г. Наконечний, П.М. Зінько, Т.П. Зінько, Ю.М. Шевчук   +3 more
doaj   +1 more source

Linear forms in the logarithms of three positive rational numbers [PDF]

Journal de théorie des nombres de Bordeaux, 1997
In this paper we prove a lower bound for the linear dependence of three positive rational numbers under certain weak linear independence conditions on the coefficients of the linear forms. Let Λ =
Bennett, Curtis D., Blass, Josef, Glass, A. M. W., Meronk, David B., Steiner, Ray P.   +4 more
openaire   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Linear forms at a basis of an algebraic number field

, 2012
It was proved by Cassels and Swinnerton-Dyer that the Littlewood conjecture in simultaneous Diophantine approximation holds for any pair of numbers in a cubic field.
de Mathan, Bernard, Bernard de Mathan
core   +1 more source

The Two-loop Anomalous Dimension Matrix for Soft Gluon Exchange [PDF]

, 2006
The resummation of soft gluon exchange for QCD hard scattering requires a matrix of anomalous dimensions. We compute this matrix directly for arbitrary 2 {yields} n massless processes for the first time at two loops.
Lance J. Dixon, S. Mert Aybat, George Sterman, Sterman, George, Aybat, S.Mert, Dixon, Lance J.   +5 more
core   +1 more source