Results 51 to 60 of about 114,855,941 (268)

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Model for allocating the share of the land component from the assessment of the market value of single real estate objects

Статистика и экономика
The objective of the study is to develop a mathematical model and corresponding methodology that allows, based on available empirical observations (market data), in a comparative approach, to create an assessment of the market value of a single real ...
V. D. Kreshchensky, D. M. Sharieva, M. B. Laskin   +2 more
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Perfect Powers in Smarandache Type Expressions [PDF]

, 2004
The author showed that there are only finitely many numbers of the above form which are products of ...
Luca, Florian
core   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Diophantine Triples and Linear Forms in Logarithms [PDF]

, 2019
This is the thesis for my master's degree in mathematics which I undertook with Dr. Omar Kihel. Over the last couple of years I have studied number theory with the aim being to develop a broader understanding of the theory of Diophantine equations ...
Earp-Lynch, Simon
core   +1 more source

Anti-collinear resummation in JIMWLK evolution in the linear regime

Journal of High Energy Physics
The recently-proposed resummation procedure for anti-collinear logarithms in the JIMWLK kernel [1] is studied in the linear (BFKL) regime in the fixed-coupling approximation.
Alex Kovner, Michael Lublinsky, Maxim Nefedov, Vladimir Skokov   +3 more
doaj   +1 more source

Hypergeometric transformations of linear forms in one logarithm

Functiones et Approximatio Commentarii Mathematici, 2008
We discuss hypergeometric constructions of rational approximations to values of the logarithm function.
Viola, Carlo, Zudilin, Wadim
openaire   +4 more sources

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

The D’Alembert Inevitability Theorem

Mathematics
We study functions satisfying the composition law F(xy)+F(x/y)=P(F(x),F(y)) with a symmetric polynomial combiner P. We prove that symmetry together with a quadratic degree bound on P forces a composition law of d’Alembert type.
Jonathan Washburn, Milan Zlatanović, Elshad Allahyarov   +2 more
doaj   +1 more source