Results 71 to 80 of about 118,710,551 (267)

Trace zero varieties in cryptography : optimal representation and index calculus [PDF]

open access: yes, 2014
The trace zero variety associated to an elliptic or hyperelliptic curve is an abelian variety defined over a finite field F_q. Its F_q-rational points yield a finite group, the trace zero subgroup of the degree zero Picard group of the original curve ...
Massierer, Maike
core   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

Evolution in opening angle combining DGLAP and BFKL logarithms [PDF]

open access: yes, 2014
We present an evolution equation which simultaneously sums the leading BFKL and DGLAP logarithms for the integrated gluon distribution in terms of a single variable, namely the emission angle of the gluon.
A. D. Martin   +5 more
core   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Diophantine Triples and Linear Forms in Logarithms [PDF]

open access: yes, 2019
This is the thesis for my master's degree in mathematics which I undertook with Dr. Omar Kihel. Over the last couple of years I have studied number theory with the aim being to develop a broader understanding of the theory of Diophantine equations and ...
Earp-Lynch, Simon
core   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Exploring the secondary school students’ experiences in the learning of logarithms in form three class; a case of a secondary school in Homa Bay County, Kenya. [PDF]

open access: yes, 2019
Mathematics is a core subject in the Kenyan education system, since it is the backbone of STEM and equips the citizens with computational skills as an ingredient for vision 2030.
Magero, Jared Odhiambo
core  

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

open access: yesMolecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim   +11 more
wiley   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba   +5 more
wiley   +1 more source

APOS analysis of students' understanding of logarithms [PDF]

open access: yes, 2007
This research is aimed at analyzing students' understanding of the concept of logarithms. Traditionally students are introduced to logarithmic functions as the inverse of exponential functions, even though logarithms were invented independently of ...
Gol Tabaghi, Shiva
core   +1 more source

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