Results 71 to 80 of about 92,871 (258)

Explicit lower bounds for linear forms in two logarithms [PDF]

Journal de théorie des nombres de Bordeaux, 2008
We give an explicit lower bound for linear forms in two logarithms. For this we specialize the so-called Schneider method with multiplicity described in [10]. We substantially improve the numerical constants involved in existing statements for linear forms in two logarithms, obtained from Baker’s method or Schneider’s method with multiplicity.
openaire   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Solving Macroeconomic Models with "Off-the-Shelf" Software: An Example of Potential Pitfalls [PDF]

When working with large-scale models or numerous small models, there can be a temptation to rely on default settings in proprietary software to derive solutions to the model. In this paper we show that, for the solution of non-linear dynamic models, this
Peter J. Stemp, Ric D. Herbert
core  

Jet substructure with analytical methods

, 2013
We consider the mass distribution of QCD jets after the application of jet substructure methods, specifically the mass-drop tagger, pruning, trimming and their variants.
Dasgupta, Mrinal, Fregoso, Alessandro, Marzani, Simone, Powling, Alexander   +3 more
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Electroweak Sudakov Logarithms and Real Gauge-Boson Radiation in the TeV Region

, 2010
Electroweak radiative corrections give rise to large negative, double-logarithmically enhanced corrections in the TeV region. These are partly compensated by real radiation and, moreover, affected by selecting isospin-noninvariant external states.
A. Denner, A. Denner, A. Denner, B. Feucht, B. Feucht, B. Jantzen, B. Jantzen, B. Jantzen, E. Maina, G. Bell, G. Degrassi, J. H. Kühn, J. Rittinger, J.H. Kuhn, J.H. Kuhn, J.H. Kuhn, J.H. Kuhn, J.H. Kuhn, J.H. Kuhn, J.H. Kuhn, J.H. Kuhn, J.H. Kuhn, J.Y. Chiu, J.Y. Chiu, J.Y. Chiu, M. Beccaria, M. Beccaria, M. Beccaria, M. Beccaria, M. Beccaria, M. Beccaria, M. Ciafaloni, M. Ciafaloni, M. Ciafaloni, M. Ciafaloni, M. Ciafaloni, M. Hori, M. Kuroda, M. Melles, P. Ciafaloni, P. Ciafaloni, P. Ciafaloni, P. Ciafaloni, R. Jackiw, R. Jackiw, S. Pozzorini, T. Kinoshita, T.D. Lee, U. Baur, V.S. Fadin, V.V. Sudakov, W. Beenakker, W. Hollik   +52 more
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Conductivity of thermally fluctuating superconductors in two dimensions

, 2003
We review recent work on a continuum, classical theory of thermal fluctuations in two dimensional superconductors. A functional integral over a Ginzburg-Landau free energy describes the amplitude and phase fluctuations responsible for the crossover from ...
Halperin, Larkin, Nelson, Prokof'ev, Prokof'ev, Sachdev, Sachdev, Subir Sachdev, Ussishkin, Wickham   +9 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source