Results 61 to 70 of about 92,871 (258)

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Infrared effects in inflationary correlation functions

open access: yes, 2010
In this article, I briefly review the status of infrared effects which occur when using inflationary models to calculate initial conditions for a subsequent hot, dense plasma phase.
Adshead A Dimastrogiovanni E   +77 more
core   +2 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Tubular approaches to Baker's method for curves and varieties

open access: yes, 2019
Baker's method, relying on estimates on linear forms in logarithms of algebraic numbers, allows one to prove in several situations the effective finiteness of integral points on varieties.
Fourn, Samuel Le
core   +2 more sources

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

High energy behaviour of gamma gamma to f f(bar) processes in SM and MSSM

open access: yes, 2001
We compute the leading logarithms electroweak contributions to gamma gamma to f f(bar) processes in SM and MSSM. Several interesting properties are pointed out, such as the importance of the angular dependent terms, of the Yukawa terms, and especially of
A. Denner   +41 more
core   +1 more source

On Algebraic Numbers of Small Height: Linear Forms in One Logarithm

open access: yesJournal of Number Theory, 1994
The authors establish a lower bound for \(|\alpha -1|\) where \(\alpha\) is a complex algebraic number \(\neq 1\). This lower bound is completely explicit in terms of the degree \(D\) of \(\alpha\) and its Mahler measure \(M(\alpha)\). Given any number \(\mu>0\) with \(\mu\geq \log M(\alpha)\), the authors prove \[ |\alpha -1|\geq \exp \Bigl\{- \bigl( \
Mignotte, M., Waldschmidt, M.
openaire   +2 more sources

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Renormalization Effects in a Dilute Bose Gas

open access: yes, 1996
The low-density expansion for a homogeneous interacting Bose gas at zero temperature can be formulated as an expansion in powers of $\sqrt{\rho a^3}$, where $\rho$ is the number density and $a$ is the S-wave scattering length.
Agustin Nieto   +12 more
core   +2 more sources

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