Results 101 to 110 of about 69,311 (291)

Fuzzy Multi-fractional Programming for Land Use Planning in Agricultural Production System

open access: yesFuzzy Information and Engineering, 2014
In this paper, we present a multi-objective linear fractional programming (MOLFP) approach for multi-objective linear fuzzy goal programming (MOLFGP) problem.
Babita Mishra   +2 more
doaj   +1 more source

Solving Integer Linear plus Linear Fractional Programs

open access: yes
Abstract The optimization of integer linear plus linear fractional programs (ILLFPs) presents significant challenges in the research field. This study introduces two innovative methods designed to efficiently address the non-convex and non-linear characteristics of ILLFPs.
Yasmine CHERFAOUI   +2 more
openaire   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

A new algorithm for generalized fractional programs [PDF]

open access: yes
A new dual problem for convex generalized fractional programs with no duality gap is presented and it is shown how this dual problem can be efficiently solved using a parametric approach. The resulting algorithm can be seen as “dual†to the Dinkelbach-
Barros, A.I.   +3 more
core   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Resolution of the linear fractional goal programming problem

open access: yesRect@, 2010
This work deals with the resolution of the goal programming problem with linear fraccional criteria. The main difficulty of these problems is the non-linear constraints of the mathematical programming models that have to be solved.
Hernández, Mónica, Caballero, Rafael
doaj  

A new exact solution method for bi-level linear fractional problems with multi-valued optimal reaction maps [PDF]

open access: yesIranian Journal of Numerical Analysis and Optimization
In many practical applications, some problems are being modeled as bilevel programming problems where the upper and lower level objectives are linear fractional functions with polyhedral constraints. If the rational reaction set of (or the set of optimal
F.Y. Feleke, S.M. Kassa
doaj   +1 more source

On duality in linear fractional programming [PDF]

open access: yesProceedings of the Indian Academy of Sciences - Section A, 1980
In this paper, a dual of a given linear fractional program is defined and the weak, direct and converse duality theorems are proved. Both the primal and the dual are linear fractional programs. This duality theory leads to necessary and sufficient conditions for the optimality of a given feasible solution. A unmerical example is presented to illustrate
openaire   +3 more sources

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

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