Results 131 to 140 of about 6,627 (303)

Crisp-linear-and Models in Fuzzy Multiple Objective Linear Fractional Programming [PDF]

open access: yes, 2020
The aim of this paper is to introduce two crisp linear models to solve fuzzy multiple objective linear fractional programming problems. In a novel manner we construct two piece-wise linear membership functions to describe the fuzzy goal linked to a ...
Stanojevic, Bogdana   +2 more
core  

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

A Study of Linear and Linear Fractional Extreme Point Programming Problems

open access: yes, 2012
M.Sc. (Mathematics and Computing)An extreme point programming problems can be defined in which an objective function is optimized over a convex polyhedron with an additional requirement that optimal solution must also be an extreme point of another ...
Garg, Neha
core  

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

open access: yesFEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara   +3 more
wiley   +1 more source

Generalized linear fractional programming under interval uncertainty

open access: yes
Data in many real-life engineering and economical problems suffer from inexactness. Herein we assume that we are given some intervals in which the data can simultaneously and independently perturb.
Hladík, Milan
core  

Methods for solving multi-objective linear fractional programming problems

open access: yes, 2013
Maģistra darbs ir veltīts lineāri racionālās programmēšanas uzdevumiem. Tiek apskatīti uzdevumi ar vienu un ar vairākām mērķa funkcijām, tai skaitā, kad tās ir sadalītas hierarhiskā struktūrā.
Balode, Daina
core  

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

On Nonlinear Fractional Programming

open access: yes
The main purpose of this paper is to delineate an algorithm for fractional programming with nonlinear as well as linear terms in the numerator and denominator. The algorithm presented is based on a theorem by Jagannathan (Jagannathan, R. 1966.
Werner Dinkelbach
core   +1 more source

A fractional programming approach for choice-based network revenue management [PDF]

open access: yes, 2009
Choice-based revenue management -- Linear fractional programming -- General Form -- Linear fractional programming -- Single ratio -- Linear fractional programming -- Sum of several ratios -- Problem description and solution approaches -- Choice-based ...
Hosseinalifam, Morad
core  

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