Results 141 to 150 of about 6,627 (303)

Branch and bound algorithm for discrete multi- level linear fractional programming problem

open access: yes, 2018
An algorithm is proposed to find an integer solution for bilevel linear fractional programming problem with discrete variables. The method develops a cut that removes the integer solutions which are not bilevel feasible.
Arora, R., Gupta, K.
core   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Outer Space Branch-and-Search Method to Tackle a Class of Linear Fractional Programming Problems and Application in Investment Decision-Making

open access: yesAxioms
This paper proposes an outer space branch-and-search method for a class of linear fractional programming problems over a polytope. First, the original problem is reformulated in an equivalent problem by applying the equivalent transformation.
Xuefeng Yao, Yusi Yang, Hongwei Jiao
doaj   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

On Linear Fractional Programming

open access: yesOn Linear Fractional Programming
Article Type ...
openaire  

Solving Multi-Objective Linear plus Linear Fractional Programming Problem

open access: yes, 2015
Multi-objective Programming Problem consists of conflicting objective functions, therefore, it is not necessary that optimum solution for one objective is also optimum for other objectives.
Gupta, Neha   +3 more
core  

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

open access: yesAging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel   +4 more
wiley   +1 more source

An Interior-point Method for Generalized Linear-fractional Programming

open access: yes, 1995
We develop an interior-point polynomial-time algorithm for a generalized linear-fractional problem. The latter problem can be regarded as a nonpolyhedral extension of the usual linear-fractional programming; typical example (which is of interest for ...
Nesterov, Yurii, Nemirovskii, AS.
core  

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang   +10 more
wiley   +1 more source

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