Results 51 to 60 of about 6,627 (303)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Revised Harmonious Fuzzy Technique for Solving Fully Fuzzy Multi-Objective Linear Fractional Programming Problems

open access: yesZanco Journal of Pure and Applied Sciences
    The revised harmonious fuzzy technique (RHFT) is a method used to solve fuzzy optimization problems. It was capitalized as an extension of the classical linear programming technique to handle constraints and objectives that are fuzzy. The harmonious
Maher A. Nawkhass
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Conditions and a computation method of the constrained regulation problem for a class of fractional-order nonlinear continuous-time systems

open access: yesInternational Journal of Applied Mathematics and Computer Science, 2021
The constrained regulation problem (CRP) for fractional-order nonlinear continuous-time systems is investigated. New existence conditions of a linear feedback control law for a class of fractional-order nonlinear continuous-time systems under constraints
Si Xindong, Yang Hongli, Ivanov Ivan G.
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

A Proposal to the Solution of Multiobjective Linear Fractional Programming Problem

open access: yesAbstract and Applied Analysis, 2013
We have proposed a new solution to the Multiobjective Linear Fractional Programming Problem (MOLFPP). The proposed solution is based on a theorem that deals with nonlinear fractional programming with single objective function and studied in the work by ...
Nuran Güzel
doaj   +1 more source

On tropical fractional linear programming

open access: yesLinear Algebra and its Applications, 2014
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Vinicius Mariano Gonçalves   +2 more
openaire   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

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