Results 81 to 90 of about 69,311 (291)

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Fractional CCP: A Fuzzy Goal Programming Approach

International Journal of Industrial Engineering and Production Research, 2014
It is the purpose of this article to introduce a linear approximation technique for solving a fractional chance constrained programming (CC) problem. For this purpose, a fuzzy goal programming model of the equivalent deterministic form of the fractional ...
Yahia Zare Mehrjerdi
doaj  

Some approaches to solving fuzzy linear fractional programming

Wasit Journal of Computer and Mathematics Science
An important planning tool is linear fuzzy fractional programming, it is used in various fields such as business, engineering, and others. We are trying to get one of the direct and effective methods that contain some arithmetic operations to obtain the
Waleed Mohammed Elaibi Elaibi, Hadi Nasseri   +1 more
doaj   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

FINANCIAL STRUCTURE OPTIMIZATION BY USING A GOAL PROGRAMMING APPROACH

Croatian Operational Research Review, 2012
This paper proposes a new methodology for solving the multiple objective fractional linear programming problems using Taylor’s formula and goal programming techniques.
Tunjo Perić, Zoran Babić
doaj  

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Fuzzy goal programming approach for solving linear fractional programming problems with fuzzy conditions [PDF]

Journal of Fuzzy Extension and Applications
Predicting the exact outcome of a real-life problem, which may occur in various fields like the industrial or healthcare sector, is challenging. Due to high information uncertainty and complicated factors influencing the industrial sector, traditional ...
Rajeev Prasad, Indrani Maiti, Sapan Das, Surapati Pramanik, Tarni Mandal   +4 more
doaj   +1 more source

An SDP Approach For Solving Quadratic Fractional Programming Problems [PDF]

, 2014
This paper considers a fractional programming problem (P) which minimizes a ratio of quadratic functions subject to a two-sided quadratic constraint. As is well-known, the fractional objective function can be replaced by a parametric family of quadratic ...
Nguyen, Van-Bong, Sheu, Ruey-Lin, Xia, Yong   +2 more
core  

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Multiparametric linear fractional functionals programming

Trabajos de Investigacion Operativa, 1989
Summary: A multiparametric linear fractional functionals program, with parameters appearing only in the objective function, is generated. The optimum solution of this parametric program is supposed to satisfy the constraints as equations only. It is also shown that the set of parameters forms a convex polyhedron.
openaire   +3 more sources