Results 41 to 50 of about 5,191,119 (260)

Fitting Additive Binomial Regression Models with the R Package blm

Journal of Statistical Software, 2013
The R package blm provides functions for fitting a family of additive regression models to binary data. The included models are the binomial linear model, in which all covariates have additive effects, and the linear-expit (lexpit) model, which allows ...
Stephanie Kovalchik, Ravi Varadhan
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Learning Heterogeneity in Causal Inference Using Sufficient Dimension Reduction

Journal of Causal Inference, 2019
Often the research interest in causal inference is on the regression causal effect, which is the mean difference in the potential outcomes conditional on the covariates. In this paper, we use sufficient dimension reduction to estimate a lower dimensional
Luo Wei, Wu Wenbo, Zhu Yeying
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

On Bayesian inference with conjugate priors for scale mixtures of normal distributions [PDF]

, 2010
Bayesian inference is considered for the multivariate regression model with distribution of the random responses belonging to the multivariate scale mixtures of normal distributions.
Ng, V.M.
core  

The Regressinator: A Simulation Tool for Teaching Regression Assumptions and Diagnostics in R

Journal of Statistics and Data Science Education
When students learn linear regression, they must learn to use diagnostics to check and improve their models. Model-building is an expert skill requiring the interpretation of diagnostic plots, an understanding of model assumptions, the selection of ...
Alex Reinhart
doaj   +1 more source

Wavelet discrete transform, ANFIS and linear regression for short-term time series prediction of air temperature

IJAIN (International Journal of Advances in Intelligent Informatics), 2017
This paper investigates the ability of Discrete Wavelet Transform and Adaptive Network-Based Fuzzy Inference System in time-series data modeling of weather parameters.
Devi Munandar
doaj   +1 more source

Modeling the Household Income Expended on Food in Egypt: A Beta Regression Approach [PDF]

The Egyptian Statistical Journal, 2014
The Beta distribution is a highly flexible parametric distribution, able to accommodate both unimodal and bimodal densities with varying severity of skewness.
Magda Mohamed Mohamed Hagag
doaj   +1 more source