Results 61 to 70 of about 460,060 (291)

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

open access: yesAging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss   +12 more
wiley   +1 more source

The Regressinator: A Simulation Tool for Teaching Regression Assumptions and Diagnostics in R

open access: yesJournal of Statistics and Data Science Education
When students learn linear regression, they must learn to use diagnostics to check and improve their models. Model-building is an expert skill requiring the interpretation of diagnostic plots, an understanding of model assumptions, the selection of ...
Alex Reinhart
doaj   +1 more source

Foot Strike Angle Prediction and Pattern Classification Using LoadsolTM Wearable Sensors: A Comparison of Machine Learning Techniques

open access: yesSensors, 2020
The foot strike pattern performed during running is an important variable for runners, performance practitioners, and industry specialists. Versatile, wearable sensors may provide foot strike information while encouraging the collection of diverse ...
Stephanie R. Moore   +5 more
doaj   +1 more source

Penalized log-likelihood estimation for partly linear transformation models with current status data

open access: yes, 2006
We consider partly linear transformation models applied to current status data. The unknown quantities are the transformation function, a linear regression parameter and a nonparametric regression effect.
Kosorok, Michael R., Ma, Shuangge
core   +1 more source

Prognostic Implications of Sleep Architecture for Patients Admitted to the Intensive Care Unit With Status Epilepticus

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Status epilepticus (SE) is associated with significant mortality. Sleep architecture may reflect normal brain function. Impaired sleep architecture is associated with poorer outcomes in numerous conditions. Here we investigate the association of sleep architecture in continuous EEG (cEEG) with survival in SE.
Ran R. Liu   +5 more
wiley   +1 more source

Linear Regression and Its Inference on Noisy Network-Linked Data

open access: yesJournal of the Royal Statistical Society Series B: Statistical Methodology, 2022
AbstractLinear regression on network-linked observations has been an essential tool in modelling the relationship between response and covariates with additional network structures. Previous methods either lack inference tools or rely on restrictive assumptions on social effects and usually assume that networks are observed without errors.
Le, Can M., Li, Tianxi
openaire   +2 more sources

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi   +2 more
wiley   +1 more source

Patterns of Postictal Abnormalities in Relation to Status Epilepticus in Adults

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Abnormalities on peri‐ictal diffusion‐weighted magnetic resonance imaging (DWI‐PMAs) are well‐established for patients with status epilepticus (SE), but knowledge on patterns of DWI‐PMAs and their prognostic impact is sparse. Methods This systematic review and individual participant data meta‐analysis included observational studies ...
Andrea Enerstad Bolle   +11 more
wiley   +1 more source

Shared Genetic Effects and Antagonistic Pleiotropy Between Multiple Sclerosis and Common Cancers

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epidemiologic studies have reported inconsistent altered cancer risk in individuals with multiple sclerosis (MS). Factors such as immune dysregulation, comorbidities, and disease‐modifying therapies may contribute to this variability.
Asli Buyukkurt   +5 more
wiley   +1 more source

Developing a simple artificial intelligence fuzzy-based model for estimating saturated hydraulic conductivity of soil

open access: yesScientific Reports
Saturated hydraulic conductivity is one of the important physical properties of soil in modeling water and solute transport, irrigation management, and drainage issues. Laboratory and field methods for directly measuring this parameter are time-consuming
Mohammad Naderianfar
doaj   +1 more source

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