Results 101 to 110 of about 560,929 (291)

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Analysis of relaxation time dependences on influencing factors in conducting oxides based on SnO2:Sb

open access: yesИзвестия высших учебных заведений. Поволжский регион: Физико-математические науки
Background. Transparent conducting oxides (TCOs) based on SnO₂:Sb are promising materials for transparent electrodes in optoelectronic devices. Understanding the mechanisms of charge carrier conductivity and relaxation in these materials is crucial for ...
T.O. Zinchenko   +5 more
doaj   +1 more source

Fast Path-Planning Algorithm for Mobile Robots via Straight Strategy

open access: yesApplied Sciences
RRT*, which augments the RRT with the ChooseParent and Rewire steps, is a widely used algorithm for path planning. RRT*-based algorithms are effective for improving the quality of paths in the Rewire step.
Jihong Jeong, Jin-Woo Jung
doaj   +1 more source

Stable, simultaneous and proportional 4-DoF prosthetic hand control via synergy-inspired linear interpolation: a case series. [PDF]

open access: yesJ Neuroeng Rehabil, 2021
Lukyanenko P   +5 more
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Sampling Theorems Associated with Offset Linear Canonical Transform by Polar Coordinates

open access: yesFractal and Fractional
The sampling theorem for the offset linear canonical transform (OLCT) of bandlimited functions in polar coordinates is an important signal analysis tool in many fields of signal processing and optics.
Hui Zhao, Bing-Zhao Li
doaj   +1 more source

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