Results 91 to 100 of about 3,175,086 (283)
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Arboviruses such as dengue, Zika, and chikungunya present similar symptoms in the early stages, which complicates their differential and timely diagnosis. In 2022, the PAHO published a guide to address this challenge. This study proposes a methodological
Wilson Arrubla-Hoyos +2 more
doaj +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
An Improved Diffusion Model for Generating Images of a Single Category of Food on a Small Dataset
In the era of the digital food economy, high-fidelity food images are critical for applications ranging from visual e-commerce presentation to automated dietary assessment.
Zitian Chen +3 more
doaj +1 more source
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
Fast Path-Planning Algorithm for Mobile Robots via Straight Strategy
RRT*, which augments the RRT with the ChooseParent and Rewire steps, is a widely used algorithm for path planning. RRT*-based algorithms are effective for improving the quality of paths in the Rewire step.
Jihong Jeong, Jin-Woo Jung
doaj +1 more source
A Triangular Prism Spatial Interpolation Method for Mapping Geological Property Fields
: The spatial interpolation of property fields in 3D, such as the temperature, salinity, and organic content of ocean water, is an active area of research in the applied geosciences.
Yang Cui +7 more
doaj +1 more source
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani +9 more
wiley +1 more source
Reading the Moody chart with a linear interpolation method. [PDF]
Huang S.
europepmc +1 more source
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source

