The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley +1 more source
Bitangential interpolation in generalized Schur classes
Bitangential interpolation problems in the class of matrix valued functions in the generalized Schur class are considered in both the open unit disc and the open right half plane, including problems in which the solutions is not assumed to be holomorphic
A. Amirshadyan +30 more
core +3 more sources
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Systems theoretic methods in decoding [PDF]
In this paper we show how ideas based on system theoretic modeling of linear behaviors may be used for decoding of linear codes. In particular we show how Sudan's bivariate interpolation approach to list decoding of RS codes allows a system theoretic ...
Kuijper, M., Polderman, J.W.
core +2 more sources
Nevanlinna-Pick Interpolation and Factorization of Linear Functionals
If $\fA$ is a unital weak-$*$ closed algebra of multiplication operators on a reproducing kernel Hilbert space which has the property $\bA_1(1)$, then the cyclic invariant subspaces index a Nevanlinna-Pick family of kernels.
Davidson, Kenneth R., Hamilton, Ryan
core +1 more source
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Counterexample-Guided Polynomial Loop Invariant Generation by Lagrange Interpolation
We apply multivariate Lagrange interpolation to synthesize polynomial quantitative loop invariants for probabilistic programs. We reduce the computation of an quantitative loop invariant to solving constraints over program variables and unknown ...
A Chakarov +23 more
core +1 more source
Model Order Reduction of Non-Linear Magnetostatic Problems Based on POD and DEI Methods [PDF]
In the domain of numerical computation, Model Order Reduction approaches are more and more frequently applied in mechanics and have shown their efficiency in terms of reduction of computation time and memory storage requirements. One of these approaches,
CLENET, Stéphane, HENNERON, Thomas
core +3 more sources
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Spatial analysis of precipitation in a high-mountain region: exploring methods with multi-scale topographic predictors and circulation types [PDF]
Statistical models of the relationship between precipitation and topography are key elements for the spatial interpolation of rain-gauge measurements in high-mountain regions.
D. Masson, C. Frei
doaj +1 more source

